Crisaborole Impurity 69 CAS CATO-C4X-202169
| CAS No. | CATO-C4X-202169 |
| Molecular Formula | C14H14BrNO2 |
| Molecular Weight | 308.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C14H14BrNO2, Crisaborole Impurity 69 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 308.17 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Crisaborole Impurity 69 (CAS CATO-C4X-202169) is a certified pharmaceutical impurity reference standard with the molecular formula C14H14BrNO2 and a molecular weight of 308.17 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Crisaborole Impurity 69 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H14BrNO2 |
| Molecular Weight | 308.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Crisaborole Standards
- Crisaborole Impurity 51 (CAS 2925547-76-6)
- Crisaborole Impurity 60 (CAS CATO-C4X-202160)
- Crisaborole Impurity 23 (CAS CATO-C4X-202123)
- Crisaborole Impurity 24 (CAS CATO-C4X-202124)
- Crisaborole Impurity 25 (CAS CATO-C4X-202125)
- Crisaborole impurity 120 (CAS CATO-C4X-2021120)
- Crisaborole Impurity 31 (CAS CATO-C4X-202131)
- Crisaborole Impurity 67 (CAS CATO-C4X-202167)
Recommended Standards
- tert-Butyl 7-bromoisoquinoline-3-carboxylate (CAS 2089316-26-5)
- Ethacrynic Acid-d5 (CAS 1330052-59-9)
- tert-Butyl 6-bromoquinoline-4-carboxylate (CAS 2374782-77-9)
- 2-(3-Methoxy-4-(2-methoxyethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1005010-05-8)
- Lefamulinum Impurity 9 (CAS CATO-C4X-30479)
- Posaconazole Impurity 197 (CAS CATO-C4X-1208197)
- Hydantoin Impurity 29 (CAS 4371-32-8)
- 2-(2-(tert-Butyl)phenoxy)pyridin-3-amine (CAS 861673-68-9)
- N,N-Dinitroso Tucatinib (CAS CATO-C4X-260524)
- (6-(Pentylthio)-9H-purin-9-yl)methanol (CAS 14133-09-6)
- Methyl (2S)-2-{[(tert-butoxy)carbonyl]amino}-4-methanesulfinylbutanoate (CAS 63701-09-7)
- 3-(Chloromethyl)-5-phenylisoxazole (CAS 14731-10-3)
- Fosaprepitant Impurity 5 (CAS CATO-C4X-11685)
- Galanin-Like Peptide (rat) trifluoroacetate salt (CAS 245114-97-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com