Osimertinib Impurity 35 CAS CATO-C4X-204535
| CAS No. | CATO-C4X-204535 |
| Molecular Formula | C25H29N7O2 |
| Molecular Weight | 459.54 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Osimertinib Impurity 35 (CAS CATO-C4X-204535, C25H29N7O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Osimertinib Impurity 35 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 459.54 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C25H29N7O2 |
| Molecular Weight | 459.54 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 7 |
Related Osimertinib Standards
- Osimertinib Impurity 61 (CAS CATO-C4X-204561)
- Osimertinib impurity 52 (CAS 2408329-87-1)
- Osimertinib Impurity 82 (CAS CATO-C4X-204582)
- Osimertinib Impurity 84 (CAS CATO-C4X-204584)
- Osimertinib Impurity 32 (CAS CATO-C4X-204532)
- Osimertinib Impurity 78 (CAS CATO-C4X-204578)
- Osimertinib Impurity 102 (CAS CATO-C4X-2045102)
- Osimertinib Impurity 5 (CAS 1009298-59-2)
Recommended Standards
- Trandolapril impurity (CAS CATO-C4X-177016)
- Vilazodone Impurity 19 (CAS 1588795-58-7)
- (1R,3S)-N-((4-cyano-2-(trifluoromethyl)phenyl)methyl)-3-((4-methyl-6-(methylamino)-1,3,5-triazin-2-yl)amino)cyclohexane-1-carboxamide (CAS 1142090-23-0)
- Olaparib Impurity 128 (CAS CATO-C4X-1135128)
- Ammonium Glycyrrhizate EP Impurity A (CAS CATO-C4X-25373)
- Ozenoxacin Impurity 27 (CAS CATO-C4X-279627)
- Metoclopramide impurity 63 (CAS CATO-C4X-141563)
- 3-Cyclopentyl-L-alanine (CAS 99295-82-6)
- Methyl 2-amino-3-ethoxybenzoate (CAS 1184228-27-0)
- 3-Isopropyl-5-oxa-2-azaspiro[3.4]Octan-1-one (CAS 1820716-61-7)
- Methyl 7-methoxy-1H-indole-6-carboxylate (CAS 733035-43-3)
- Ethyl 3-amino-2,2-dimethylpropanoate (CAS 59193-77-0)
- (Z)-2-(2-(((3,4-dimethoxyphenethyl)imino)methyl)-1H-pyrrol-1-yl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile (CAS 333774-47-3)
- [3-31]-Semaglutide D (CAS C152H230N42O47)
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