Ruxolitinib Impurity 135 CAS CATO-C4X-2058135
| CAS No. | CATO-C4X-2058135 |
| Molecular Formula | C6H4Br2N4 |
| Molecular Weight | 291.93 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Ruxolitinib Impurity 135 (CAS CATO-C4X-2058135), a pharmacopoeial impurity reference standard (molecular formula C6H4Br2N4, MW 291.93 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C6H4Br2N4, Ruxolitinib Impurity 135 contains a nitrile group, bromine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 291.93 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Ruxolitinib Impurity 135 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H4Br2N4 |
| Molecular Weight | 291.93 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
Related Ruxolitinib Standards
- Ruxolitinib Impurity 105 (CAS CATO-C4X-2058105)
- Ruxolitinib Impurity 225 (CAS CATO-C4X-2058225)
- Ruxolitinib Impurity 107 (CAS CATO-C4X-2058107)
- Ruxolitinib Impurity 104 (CAS CATO-C4X-2058104)
- Ruxolitinib Impurity 118 (CAS CATO-C4X-2058118)
- Ruxolitinib Impurity 63 (CAS CATO-C4X-205863)
- Ruxolitinib Impurity N3 (CAS 1643967-75-2)
- Ruxolitinib Impurity 236 (CAS CATO-C4X-2058236)
Recommended Standards
- 6,7-Dibromopyrrolo[1,2-a]pyrazin-1(2H)-one (CAS 290353-35-4)
- 2,5-Dibromo-3-(difluoromethyl)thiophene (CAS 1244041-06-2)
- 5,7-Dibromobenzo[d]isoxazol-3-amine (CAS 89583-81-3)
- 2,5-Dibromothiophene-3,4-dicarbonitrile (CAS 1056841-63-4)
- Febuxostat Impurity 89 (CAS CATO-C4X-116289)
- Salbutamol EP Impurity M (CAS 18910-70-8)
- （R)-Rasagiline Impurity 37 Mesylate (CAS CATO-C4X-191337)
- Methyl (S)-2-amino-3-(2-fluorophenyl)propanoate hydrochloride (CAS 457654-69-2)
- 2-(3-Phenylallylidene)malononitrile (CAS 5439-39-4)
- 2-(3-Acetyl-4-hydroxy-5-oxo-2-phenyl-2,5-dihydro-1H-pyrrol-1-yl)acetic acid (CAS 220128-11-0)
- Tert-butyl 4-(2-(methoxycarbonyl)benzyl)piperazine-1-carboxylate (CAS 1355334-48-3)
- {[5-(furan-2-yl)-1,3,4-oxadiazol-2-yl]methyl}(methyl)amine (CAS 1247425-24-6)
- 5-bromo-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid (CAS 916325-85-4)
- Semaglutide impurity 206 (CAS CATO-C4X-2226206)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com