Ruxolitinib Impurity 118 CAS CATO-C4X-2058118
| CAS No. | CATO-C4X-2058118 |
| Molecular Formula | C15H18N6 |
| Molecular Weight | 282.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ruxolitinib Impurity 118.
Ruxolitinib Impurity 118 (CAS CATO-C4X-2058118) is a certified pharmaceutical impurity reference standard with the molecular formula C15H18N6 and a molecular weight of 282.34 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, Ruxolitinib Impurity 118 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 282.34 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Ruxolitinib Impurity 118 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H18N6 |
| Molecular Weight | 282.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Ruxolitinib Standards
- Ruxolitinib Impurity 63 (CAS CATO-C4X-205863)
- Ruxolitinib Impurity 237 (CAS CATO-C4X-2058237)
- Ruxolitinib Impurity 107 (CAS CATO-C4X-2058107)
- Ruxolitinib Impurity 229 (CAS CATO-C4X-2058229)
- Ruxolitinib Impurity 225 (CAS CATO-C4X-2058225)
- Ruxolitinib Impurity 14 (CAS CATO-C4X-205814)
- Ruxolitinib Impurity 36 (CAS CATO-C4X-205836)
- Ruxolitinib Impurity 135 (CAS CATO-C4X-2058135)
Recommended Standards
- Trimetazidine Impurity 18 (CAS CATO-C4X-180318)
- 1,1-Azonaphthalene (CAS 487-10-5)
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- Daraxonrasib Impurity 4 (CAS CATO-C4X-35184)
- Riociguat Impurity 12 (CAS CATO-C4X-174912)
- Fosaprepitant Impurity 6 (CAS 172822-01-4（free base）)
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- 1-Methyl-3-(trifluoromethyl)cyclobutane-1-carboxylic acid (CAS 2090434-02-7)
- 1-(2-Bromoethoxy)-3-(trifluoromethyl)benzene (CAS 18800-39-0)
- 1-Amino-1H-indol-4-ol (CAS 877470-52-5)
- Ethyl 1-benzyl-5-hydroxy-1H-1,2,3-triazole-4-carboxylate (CAS 94158-08-4)
- D-Lys20-Tirzepatide (CAS CATO-CPTD788914)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com