Hydroxymethyl Ruxolitinib CAS CATO-C4X-2058216
| CAS No. | CATO-C4X-2058216 |
| Molecular Formula | C18H20N6O |
| Molecular Weight | 336.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Hydroxymethyl Ruxolitinib (CAS CATO-C4X-2058216), a certified reference material (molecular formula C18H20N6O, MW 336.39 g/mol) for analytical method development and quality control.
The molecular framework of Hydroxymethyl Ruxolitinib (C18H20N6O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Hydroxymethyl Ruxolitinib meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H20N6O |
| Molecular Weight | 336.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Hydroxymethyl Standards
- 2-(Hydroxymethyl)-4-(2-methoxybenzoyl)-6-phenylpyridazin-3(2H)-one (CAS 832712-37-5)
- 8-(4-(Hydroxymethyl)phenyl)-2-morpholino-4H-chromen-4-one (CAS 503468-78-8)
- N-(2-(Hydroxymethyl)-4,5-dimethoxyphenyl)-4-methylbenzenesulfonamide (CAS 871563-17-6)
- 2-((5-(Hydroxymethyl)-1-(2-(methylamino)-2-oxoethyl)-1H-imidazol-2-yl)thio)-N-phenylacetamide (CAS 923138-74-3)
- 4-({3-[3-(hydroxymethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl}amino)cyclohexan-1-ol (CAS 1010441-40-3)
- 2-(5-(Hydroxymethyl)-2-((3-methylbenzyl)thio)-1H-imidazol-1-yl)-N-isopropylacetamide (CAS 921867-25-6)
- 2-(5-(Hydroxymethyl)-2-((4-methylbenzyl)thio)-1H-imidazol-1-yl)-N-isopropylacetamide (CAS 921566-93-0)
- 2-(2-(3-(Hydroxymethyl)piperidin-1-yl)-1H-benzo[d]imidazol-1-yl)nicotinonitrile (CAS 1146080-74-1)
Recommended Standards
- Cefoxitin EP Impurity C（Cefalotin EP Impurity D） (CAS 10590-10-0)
- Ruxolitinib Impurity 22 (CAS CATO-C4X-205822)
- 714272-27-2 986FY7F8XR NPI 2358 Plinabulin [USAN:INN] 2,5-Piperazinedione, 3-((5-(1,1-dimethylethyl)-1H-imidazol-4-yl)methylene)-6-(phenylmethylene)-, (3Z,6Z)- NPI-2358 UNII-986FY7F8XR Plinabulin (CAS 714272-27-2)
- Ruxolitinib Impurity 4 (CAS 1236033-03-6)
- 2-Benzyl-3-oxoisoindolin-1-yl acetate (CAS 115397-98-3)
- 5-Trifluoromethyl-2H-pyridazine-2-one (CAS 244268-34-6)
- 4H,5H-[1,2,4]triazolo[1,5-a]quinazolin-5-one (CAS 73549-68-5)
- (±)-Epichlorohydrin-2-d1 (stabilized with hydroquinone) (CAS 70735-27-2)
- 2-Chloro-1-(oxan-4-yl)propan-1-one (CAS 1889187-36-3)
- 5-amino-1-(2-azatricyclo[10.4.0.0⁴⁹]hexadeca-1(12),4(9),5,7,13,15-hexaen-10-yn-2-yl)pentan-1-one (CAS 2401876-29-5)
- n-(5-Amino-2-methylphenyl)benzenesulfonamide (CAS 436089-20-2)
- 5-[(2,6-dichlorophenyl)methyl]-1,3-thiazol-2-amine (CAS 850021-38-4)
- 4-(2-Chlorophenoxy)-5,6-difluoropyrimidine (CAS 193741-72-9)
- A-18-F-NH2; Morphine Modulating Neuropeptide (CAS 99588-52-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com