Ruxolitinib Impurity 41 CAS CATO-C4X-205841

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-205841
Molecular FormulaC17H18N6O
Molecular Weight322.36 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Ruxolitinib Impurity 41 CAS CATO-C4X-205841 chemical structure

Description

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO supplies Ruxolitinib Impurity 41 (CAS CATO-C4X-205841), a pharmacopoeial impurity reference standard (molecular formula C17H18N6O, MW 322.36 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Ruxolitinib Impurity 41 (C17H18N6O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

As a certified reference material (CRM), Ruxolitinib Impurity 41 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC17H18N6O
Molecular Weight322.36 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms6

Related Ruxolitinib Standards

Recommended Standards

Why CATO?