Ruxolitinib Impurity 33 CAS 1809535-63-4
| CAS No. | 1809535-63-4 |
| Molecular Formula | C17H18N6O |
| Molecular Weight | 322.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Ruxolitinib Impurity 33 (CAS 1809535-63-4), a pharmacopoeial impurity reference standard (molecular formula C17H18N6O, MW 322.36 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Ruxolitinib Impurity 33 (C17H18N6O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Ruxolitinib Impurity 33 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H18N6O |
| Molecular Weight | 322.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 6 |
Related Ruxolitinib Standards
- Ruxolitinib Impurity N7 (Mixture of Diastereomers) (CAS 1092973-95-9)
- Ruxolitinib Impurity 116 (CAS CATO-C4X-2058116)
- Ruxolitinib Impurity 117 (CAS CATO-C4X-2058117)
- Ruxolitinib Impurity 120 (CAS 1092973-94-8)
- Ruxolitinib Impurity 32 (CAS 1315607-85-2)
- Ruxolitinib Impurity 35 (CAS CATO-C4X-205835)
- Ruxolitinib Impurity 40 (CAS CATO-C4X-205840)
- Ruxolitinib Impurity 41 (CAS CATO-C4X-205841)
Recommended Standards
- 3-Cyclopentyl-3-(4-(5-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile (CAS 1289218-88-7)
- Ruxolitinib Impurity 72 (CAS 3029006-61-6)
- Ruxolitinib Impurity 75 (CAS CATO-C4X-205875)
- Neomycin Sulfate EP Impurity A (CAS 3947-65-7)
- Solriamfetol Impurity 26 (CAS CATO-C4X-256326)
- Clopidogrel Impurity 30 (CAS 212838-70-5)
- Oseltamivir Impurity 91 (CAS CATO-C4X-172091)
- Methyl 3-[4-([1,1-biphenyl]-4-ylcarbonyl)-1H-1,2,3-triazol-1-yl]-2-thiophenecarboxylate (CAS 439111-70-3)
- 2-Chloro-1-(2-hydroxy-5-methylphenyl)ethan-1-one (CAS 22307-94-4)
- Ethyl 2'-oxospiro[cyclopropane-1,3'-indoline]-2-carboxylate (CAS 67503-06-4)
- 2-amino-3-(3,4-dihydroxy-2-methylphenyl)propanoic acid hydrobromide (CAS 897046-02-5)
- (R)-1-(3-Nitro-5-(trifluoromethyl)phenyl)ethan-1-amine (CAS 1213678-78-4)
- 4-Hydroxybenzimidamide (CAS 15535-98-5)
- Tirzepatide Impurity 20 (CAS CATO-C4X-324020)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com