Menaquinone impurity 34 CAS CATO-C4X-207634
| CAS No. | CATO-C4X-207634 |
| Molecular Formula | C22H16O4 |
| Molecular Weight | 344.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Menaquinone impurity 34 (CAS CATO-C4X-207634, C22H16O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Menaquinone impurity 34 (C22H16O4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Menaquinone impurity 34 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H16O4 |
| Molecular Weight | 344.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Menaquinone Standards
- Menaquinone impurity 24 (CAS 51921-98-3)
- Menaquinone Impurity 45 (CAS 112162-99-9)
- Menaquinone impurity 17 (CAS 62796-50-3)
- Menaquinone Impurity 12 (CAS 3790-76-9)
- Menaquinone impurity 40 (CAS 3879-62-7)
- Menaquinone impurity 41 (CAS 3879-61-6)
- Menaquinone impurity 23 (CAS 2387-69-1)
- Menaquinone Impurity 46 (CAS 57766-68-4)
Recommended Standards
- Carbocisteine Impurity 27 (CAS CATO-C4X-201027)
- N-(2-(benzo[d][1,3]dioxol-5-yl)ethyl)-N-(2,3-dimethoxybenzyl)nitrous amide (CAS CATO-CCHM706398)
- Quinolone analog 5 (CAS CATO-C4X-1074141)
- Methyl 3-methyl-1-phenyl-6-(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011399-53-3)
- Ursodeoxycholic Acid Impurity N3 (CAS 28083-34-3)
- Itraconazole EP Impurity A (CAS 252964-68-4)
- Nintedanib Impurity N2 (CAS CATO-C4X-12662)
- PSB 06126 (CAS 1052089-16-3)
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(4-methoxyphenyl)-1H-pyrrole-2-sulfonamide (CAS 321433-66-3)
- 5-Isopropyl-3-((5-methylisoxazol-3-yl)amino)cyclohex-2-en-1-one (CAS 1022698-87-8)
- 5-((3-Fluorobenzyl)thio)-1,3,4-thiadiazol-2-amine (CAS 685108-09-2)
- 1185011-66-8 2,2-Bis[(~2~H_3_)methyl]butanoyl chloride DTXSID80661936 (CAS 1185011-66-8)
- Lenacapavir Impurity 25 (CAS CATO-C4X-324825)
- Semaglutide impurity 54 (CAS CATO-C4X-222654)
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