1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(4-methoxyphenyl)-1H-pyrrole-2-sulfonamide CAS 321433-66-3
| CAS No. | 321433-66-3 |
| Molecular Formula | C17H13ClF3N3O3S |
| Molecular Weight | 431.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(4-methoxyphenyl)-1H-pyrrole-2-sulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(4-methoxyphenyl)-1H-pyrrole-2-sulfonamide (CAS 321433-66-3), molecular formula C17H13ClF3N3O3S and molecular weight 431.82 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(4-methoxyphenyl)-1H-pyrrole-2-sulfonamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 431.82 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C17H13ClF3N3O3S |
| Molecular Weight | 431.82 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- Ethyl 2-(1-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)-5-methylthiazole-4-carboxylate (CAS 1823182-96-2)
- 3-(3-(3-(2-Chloro-4-nitrophenoxy)propyl)ureido)benzene-1-sulfonyl fluoride (CAS 25240-52-2)
- 2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)ethyl 4-fluorobenzoate (CAS 338415-48-8)
- N-(3-chloro-4-fluorophenyl)-2-((3-cyano-6-ethyl-5-methyl-4-(trifluoromethyl)pyridin-2-yl)thio)acetamide (CAS 664999-23-9)
- 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(3-(4-cyanophenoxy)phenyl)urea (CAS 1400989-25-4)
- 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-1-[(1E)-{[(4-methoxyphenyl)methoxy]amino}methylidene]urea (CAS 321433-46-9)
- 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-1-[(E)-[(3-ethoxy-4-hydroxyphenyl)methylidene]amino]urea (CAS 866149-29-3)
- N-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(pyridin-3-yloxy)phenyl)-1H-1,2,4-triazol-5-amine (CAS 877874-59-4)
Recommended Standards
- Albaconazole (CAS 187949-02-6)
- Ethyl N-[(2E)-2-({4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}methylidene)-2-cyanoacetyl]carbamate (CAS 338979-07-0)
- 5-((4-Chlorophenyl)sulfinyl)-N-(3-(trifluoromethyl)phenyl)-1,2,3-thiadiazole-4-carboxamide (CAS 306977-02-6)
- 3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-1-phenyl-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile (CAS 861209-33-8)
- 4-Methyl-2H-1,2,4-benzothiadiazin-3(4H)-one-1,1-dioxide sodium salt (CAS 42140-55-6)
- 4-Methoxy-6-phenyl-5,6-dihydro-pyran-2-one (CAS 17298-18-9)
- (R)-3,3'-Bis(2-naphthyl)-5,5',6,6',7,7',8,8'-octahydro-1,1'-bi-2,2'-naphthol (CAS 922711-77-1)
- Dexpanthenol Impurity 24 (CAS CATO-C4X-161324)
- Lewis A trisaccharide methyl glycoside (CAS 186315-40-2)
- N-(3,5-dimethylphenyl)-2-((2,3,4,5,6-pentamethylbenzyl)thio)acetamide (CAS 329079-47-2)
- 2-(2-Bromo-6-(difluoromethyl)-3-fluoropyridin-4-yl)acetonitrile (CAS 1806830-63-6)
- 1-Phenyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 1185292-87-8)
- 2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyrimidine-5-carboxylic acid (CAS 253315-11-6)
- Tau Peptide (274-288) trifluoroacetate salt (CAS 330456-39-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com