Lusutrombopag Impurity 34 CAS CATO-C4X-208434
| CAS No. | CATO-C4X-208434 |
| Molecular Formula | C25H28Cl2N2O3S |
| Molecular Weight | 507.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Lusutrombopag Impurity 34 (CAS CATO-C4X-208434, C25H28Cl2N2O3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Lusutrombopag Impurity 34 (C25H28Cl2N2O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Lusutrombopag Impurity 34 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H28Cl2N2O3S |
| Molecular Weight | 507.47 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Lusutrombopag Standards
- Lusutrombopag Impurity 56 (CAS CATO-C4X-208456)
- Lusutrombopag Impurity 54 (CAS CATO-C4X-208454)
- Lusutrombopag Impurity 32 (CAS CATO-C4X-208432)
- Lusutrombopag Impurity 17 (CAS CATO-C4X-208417)
- Lusutrombopag Impurity 40 (CAS CATO-C4X-208440)
- Lusutrombopag Impurity 61 (CAS CATO-C4X-208461)
- Lusutrombopag Impurity 37 (CAS CATO-C4X-208437)
- Lusutrombopag Impurity 53 (CAS CATO-C4X-208453)
Recommended Standards
- Piroxicam O-β-D-GlucuronideDISCONTINUED, see P510015 (CAS 108929-12-0)
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- Ciprofloxacin-acyl-Beta-D-glucuronide (CAS 105029-31-0)
- Elagolix Impurity 24 (CAS CATO-C4X-206824)
- Prucalopride Impurity 54 (CAS CATO-C4X-103854)
- Tolvaptan Impurity 14 (CAS 137973-76-3)
- Tedizolid Impurity 91 (CAS 1259078-16-4)
- Dibenzo[b,d]furan-4-yldiphenylphosphine oxide (CAS 1268162-33-9)
- 2-Chloro-n-[2-(2-chlorophenyl)-2-(pyrrolidin-1-yl)ethyl]acetamide hydrochloride (CAS 1052545-91-1)
- 2-(2-(tert-Butyl)pyrimidin-5-yl)ethan-1-amine hydrochloride (CAS 1196155-56-2)
- (OC-6-22)-Tris(benzo[h]quinolin-10-yl-κC,κN)iridium (CAS 337526-98-4)
- Propionyl-d (CAS 352439-04-4)
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