Lusutrombopag Impurity 45 CAS CATO-C4X-208445
| CAS No. | CATO-C4X-208445 |
| Molecular Formula | C22H36O3 |
| Molecular Weight | 348.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Lusutrombopag Impurity 45 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Lusutrombopag Impurity 45 (CAS CATO-C4X-208445, C22H36O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Lusutrombopag Impurity 45 (C22H36O3) contains a steroid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 348.52 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C22H36O3 |
| Molecular Weight | 348.52 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Lusutrombopag Standards
- Lusutrombopag Impurity 86 (CAS CATO-C4X-208486)
- Lusutrombopag Impurity 52 (CAS CATO-C4X-208452)
- Lusutrombopag Impurity N4 (CAS 1110767-98-0)
- Lusutrombopag Impurity 9 (CAS CATO-C4X-20849)
- Lusutrombopag Impurity 25 (CAS CATO-C4X-208425)
- Lusutrombopag Impurity 51 (CAS CATO-C4X-208451)
- Lusutrombopag Impurity 30 (CAS 1110767-19-5)
- Lusutrombopag Impurity 87 (CAS CATO-C4X-208487)
Recommended Standards
- 52694-55-0 Q2640DPW33 (+,-)-1-Cyclohexyl-4-(1,2-diphenylethyl)piperazine Piperazine, 1-cyclohexyl-4-(1,2-diphenylethyl)-, (+-)- (+-)-1-Cyclohexyl-4-(1,2-diphenylethyl)piperazine MT 45 IC 6 IC 6 (analgesic) MT-45 UNII-Q2640DPW33 (CAS 52694-55-0)
- Anacardic Acid (CAS 16611-84-0)
- Larixyl acetate (CAS 4608-49-5)
- N-Cycloheptyl-3-(2-methyl-4-(thiophen-2-yl)thiazol-5-yl)propanamide (CAS 1049030-55-8)
- Dopamine Impurity 81 (CAS 68929-11-3)
- Minoxidil Impurity 52 (CAS CATO-C4X-170052)
- Exemestane Impurity 19 (CAS CATO-C4X-164119)
- 1-(5-Isopropoxypyridin-2-yl)ethanone (CAS 1198166-03-8)
- 1-((Diethylamino)methyl)cyclopentan-1-amine dihydrochloride (CAS 2098054-00-1)
- (2-(2-(Isopropylthio)pyridin-3-yl)pyrrolidin-1-yl)(phenyl)methanone (CAS 1352514-53-4)
- 2-(2,6-Dichlorophenyl)-2,2-difluoroethan-1-ol (CAS 1824000-39-6)
- 2-Amino-6-ethyl-N-(4-methylbenzyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide (CAS 725226-66-4)
- 2-((Methylamino)methyl)quinazolin-4-amine (CAS 1049606-68-9)
- Semaglutide impurity 269 (CAS CATO-C4X-2226269)
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