Lusutrombopag Impurity 7 CAS CATO-C4X-20847
| CAS No. | CATO-C4X-20847 |
| Molecular Formula | C31H36Cl2N2O5S |
| Molecular Weight | 619.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Lusutrombopag Impurity 7 (CAS CATO-C4X-20847, C31H36Cl2N2O5S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, Lusutrombopag Impurity 7 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 619.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C31H36Cl2N2O5S |
| Molecular Weight | 619.60 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Lusutrombopag Standards
- Lusutrombopag Impurity 19 (CAS 1110768-00-7)
- Lusutrombopag Impurity 39 (CAS CATO-C4X-208439)
- Lusutrombopag Impurity 8 (CAS CATO-C4X-20848)
- Lusutrombopag Impurity 55 (CAS CATO-C4X-208455)
- Lusutrombopag Impurity 57 (CAS CATO-C4X-208457)
- Lusutrombopag Impurity 58 (CAS CATO-C4X-208458)
- Lusutrombopag Impurity 81 (CAS CATO-C4X-208481)
- Lusutrombopag Impurity 82 (CAS CATO-C4X-208482)
Recommended Standards
- (11bR)-2,6-bis(3,5-difluorophenyl)-3,3,5,5-tetraoxide-dinaphtho[2,1-d:1',2'-f][1,3,2]dithiazepine (CAS 1245748-62-2)
- Thalidomide-O-PEG4-NHS ester (CAS 2411681-88-2)
- (11bR)-N-[(1S)-1-[2-(Diphenylphosphino)phenyl]ethyl]dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine (CAS 913265-30-2)
- 2-Acetamido-2-deoxy-3-O-(α-L-fucopyranosyl)-D-glucopyranose Pentaacetate (CAS 309263-13-6)
- Niraparib Impurity N10 HCl (CAS 2409590-07-2)
- Rimegepant Impurity 62 (CAS 63031-32-3)
- Domperidone EP Impurity A (CAS 53786-28-0)
- 5-Ethyl-1-methyl-1,2,3,4-tetrazole 5-ethyl-1-methyl-1H-tetrazole 90329-50-3 (CAS 90329-50-3)
- 1-(4-Methylphenyl)-1h-pyrazole-4-sulfonyl chloride (CAS 1156916-73-2)
- 1-(4-Chloro-3-fluorophenyl)propan-2-ol (CAS 1443340-73-5)
- 3,3-Bis(3,5-dibromo-4-hydroxyphenyl)isobenzofuran-1(3H)-one (CAS 76-62-0)
- 5-(Methylthio)pentan-2-amine (CAS 57774-98-8)
- (R)-2-Amino-2-(3-(methylthio)phenyl)ethanol hydrochloride (CAS 2442565-24-2)
- Peptide Impurity 11 X TFA Salt (CAS CATO-CPTD788811)
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