Remdesivir Impurity 27 CAS CATO-C4X-210027
| CAS No. | CATO-C4X-210027 |
| Molecular Formula | C27H35N6O8P |
| Molecular Weight | 602.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Remdesivir Impurity 27.
As a process- or degradation-related impurity, Remdesivir Impurity 27 (CAS CATO-C4X-210027, C27H35N6O8P) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Remdesivir Impurity 27 (C27H35N6O8P) contains a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 13.5, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 602.58 g/mol, it falls into the high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Remdesivir Impurity 27 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H35N6O8P |
| Molecular Weight | 602.58 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Remdesivir Standards
- Remdesivir (CAS 1809249-37-3)
- Remdesivir Impurity 28 (CAS CATO-C4X-210028)
- Remdesivir Impurity 31 (CAS CATO-C4X-210031)
- Remdesivir-d4 (CAS CATO-C4X-210043)
- Remdesivir Impurity 49 (CAS CATO-C4X-210049)
- Remdesivir Impurity 50 (CAS CATO-C4X-210050)
- Remdesivir Impurity 42 (CAS 1191237-66-7)
- Remdesivir Impurity 26 (CAS CATO-C4X-210026)
Recommended Standards
- Etoposide EP Impurity I (CAS 111712-42-6)
- Flurbiprofen Impurity 126 (CAS CATO-C4X-1444126)
- 2,9-Bis(4-methoxyphenyl)anthra[2,1,9-def:6,5,10-d'e'f']diisoquinoline-1,3,8,10(2H,9H)-tetraone (CAS 6424-77-7)
- 2,2'-[(11bS)-4-Hydroxy-4-oxidodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-2,6-diyl]bis[quinoline] (CAS 1502024-23-8)
- Posaconazole impurity 226 (CAS CATO-C4X-1208226)
- Brimonidine EP Impurity G HCl (CAS CATO-C4X-156637)
- Risedronate EP Impurity A (CAS 1486617-90-6)
- Isoxsuprine-d6 HCl(mixture of diastereomers) (CAS 2706004-35-3)
- Ethyl 7-[4-(N,N-dimethylamino)phenyl]-7-oxoheptanoate (CAS 91727-04-7)
- 1-[3-(aminomethyl)phenyl]ethan-1-one hydrochloride (CAS 149889-64-5)
- ethyl-3-aminocrotonate (CAS 3222-57-9)
- (S)-N-(2-Chloro-6-fluorobenzyl)pyrrolidin-3-amine hydrochloride (CAS 1289585-05-2)
- 1-(Difluorophenylmethyl)-2-methylbenzene (CAS 1204295-98-6)
- D-γ-Glu20-Side-Tirzepatide (CAS CATO-CPTD788929)
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