Linaclotide impurity 33 CAS CATO-C4X-210633
| CAS No. | CATO-C4X-210633 |
| Molecular Formula | C60H79N15O22S6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Linaclotide impurity 33 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 1554.73 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Linaclotide impurity 33 (CAS CATO-C4X-210633, C60H79N15O22S6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C60H79N15O22S6 |
| Molecular Weight | 1554.73 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 29.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 15 |
| Sulfur Atoms | 6 |
Related Linaclotide Standards
- Linaclotide impurity 17 (CAS 1092457-78-7)
- Linaclotide impurity 35 (CAS 1207977-38-5)
- Linaclotide impurity 45 (CAS 1331835-31-4)
- Linaclotide impurity 43 (CAS 1422389-15-8)
- Linaclotide impurity 44 (CAS 1422389-16-9)
- Linaclotide (CAS 851199-59-2)
- Linaclotide acetate (CAS 851199-59-2(free base))
- Linaclotide Acetate - API Standards (CAS 851199-60-5)
Recommended Standards
- Meloxicam impurity 14 (CAS 91-25-8)
- Cholic Acid Impurity 46 (CAS 3081473-18-6)
- Vitamin A EP Impurity C（Mixture of Z and E Isomers） (CAS 16729-22-9 ((3E)-Isomer))
- 2-(3,5-Difluoro-2-propoxyphenyl)ethan-1-ol (CAS 1443336-13-7)
- 4,4-Difluoro-3-(4-methoxyphenyl)butanoic acid (CAS 1638757-34-2)
- 2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-2-(4-methoxyphenyl)aceticacid (CAS 868260-17-7)
- (2E)-3-(2H-1,3-Benzodioxol-5-yl)-N-(4-fluorophenyl)prop-2-enamide (CAS 298215-60-8)
- 6-Amino-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 1018135-49-3)
- Cyclopentyl(2,5-dimethylphenyl)methanone (CAS 27586-77-2)
- Adrenal Peptide E, bovine (CAS 78355-50-7)
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