Gadobutrol Impurity 126 CAS CATO-C4X-2120126
| CAS No. | CATO-C4X-2120126 |
| Molecular Formula | C12H24N4O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Gadobutrol Impurity 126 (CAS CATO-C4X-2120126, C12H24N4O4HClH2O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Gadobutrol Impurity 126 (C12H24N4O4HClH2O) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 1.0, corresponding to approximately 1 ring(s) or double-bond equivalent(s). With a molecular weight of 342.82 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H24N4O4 4*HCl H2O |
| Molecular Weight | 342.82 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Gadobutrol Standards
- Gadobutrol Impurity 112 (CAS 1003-83-4)
- Gadobutrol Impurity 12 4HCl (CAS 10045-25-7)
- Gadobutrol Impurity 79 (CAS 105855-71-8)
- Gadobutrol Impurity 115 (CAS 112-24-3)
- Gadobutrol EP Impurity C (Gadoteridol USP Related Compound B) (CAS 112188-16-6)
- Gadobutrol Impurity N5 (CAS 112193-75-6)
- Gadobutrol Impurity 104 4HCl (CAS 112193-75-6（free base）)
- Gadobutrol Impurity 37 (Cyclen Disulfate) (CAS 112193-77-8)
Recommended Standards
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- N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)hexanamide (CAS 63844-89-3)
- 2-Ethyl-6-hydroxybenzoic acid (CAS 59681-42-4)
- (1E,3E,5E,7E,9E)-1,10-Diphenyldeca-1,3,5,7,9-pentaene (CAS 3029-41-2)
- 1-(2-Chlorobenzyl)-3-(3-(trifluoromethyl)phenyl)urea (CAS 897540-69-1)
- (1R,3S,5R)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylic Acid (CAS 197142-34-0)
- Ethyl (1S,2S)-2-(4-acetyl-3-fluorophenyl)cyclopropane-1-carboxylate (CAS 2431996-89-1)
- TRAF6 Control Peptide trifluoroacetate salt (CAS 852690-80-3)
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