Calcitriol Impurity 25 CAS 134523-84-5
| CAS No. | 134523-84-5 |
| Molecular Formula | C27H44O3 |
| Molecular Weight | 416.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Calcitriol Impurity 25 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Calcitriol Impurity 25 (CAS 134523-84-5) is a certified pharmaceutical impurity reference standard with the molecular formula C27H44O3 and a molecular weight of 416.64 g/mol.
Structurally, Calcitriol Impurity 25 (C27H44O3) contains a steroid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 416.64 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C27H44O3 |
| Molecular Weight | 416.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
Related Calcitriol Standards
- Calcitriol (CAS 32222-06-3)
- Calcitriol Impurity 26 (CAS 57102-09-7)
- Calcitriol Impurity 27 (CAS CATO-C4X-151027)
- Calcitriol Impurity 29 (CAS 96614-28-7)
- Calcitriol Impurity 31 (CAS 96862-25-8)
- Calcitriol impurity 37 (CAS CATO-C4X-151037)
- Calcitriol Impurity 38 (CAS CATO-C4X-151038)
- Calcitriol EP Impurity A (CAS 73837-24-8)
Recommended Standards
- Alfacalcidol impurity 17 (CAS 2227309-93-3)
- Paricalcitol Impurity 9 (CAS 216161-87-4)
- Paricalcitol Impurity 8 (CAS CATO-C4X-13878)
- Paricalcitol Impurity 5 (CAS CATO-C4X-13875)
- Propylthiouracil EP Impurity A (CAS 62-56-6)
- Ofloxacin EP Impurity E (CAS 82419-52-1)
- Temozolomide Impurity 7 (CAS CATO-C4X-13537)
- 2-methanesulfinyl-6-methylaniline hydrochloride (CAS 1797061-46-1)
- 4-(Bicyclo[1.1.1]Pentan-1-yl)benzonitrile (CAS 1823925-04-7)
- N-Benzyl-3-ethoxy-2-propyl-2H-indazole-6-carboxamide (CAS 919108-02-4)
- 3-Amino-5-nitropyridine Hydrochloride (CAS 1220040-21-0)
- N-Cyclohexyl-2-bromo-5-fluorobenzamide (CAS 951884-99-4)
- 3-(Methylsulfanyl)-4-(3-phenyl-1,2,4-oxadiazol-5-yl)-1h-pyrazol-5-amine (CAS 1188304-89-3)
- Semaglutide impurity 50 (CAS 2773558-66-8)
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