Sivelestat impurity 37 CAS CATO-C4X-212337
| CAS No. | CATO-C4X-212337 |
| Molecular Formula | C25H24N4O5 |
| Molecular Weight | 460.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Sivelestat impurity 37 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Sivelestat impurity 37 (CAS CATO-C4X-212337, C25H24N4O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Sivelestat impurity 37 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 460.48 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C25H24N4O5 |
| Molecular Weight | 460.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Sivelestat Standards
- Sivelestat Impurity 9 (CAS 1094231-79-4)
- Sivelestat sodium Impurity 5 (CAS 127373-95-9)
- Sivelestat Impurity 24 (CAS CATO-C4X-212324)
- Sivelestat impurity 36 (CAS CATO-C4X-212336)
- Sivelestat (CAS 127373-66-4)
- Sivelestat Impurity 6 (CAS CATO-C4X-21236)
- Sivelestat Impurity 33 (CAS CATO-C4X-212333)
- Sivelestat Impurity 7 (CAS 1071827-84-3)
Recommended Standards
- Apixaban Impurity 1 (CAS 503614-92-4)
- Fmoc-Orn(pyrazinylcarbonyl)-OH (CAS 201046-61-9)
- Tadalafil Impurity 110 (CAS CATO-C4X-1087110)
- (E)-N-(4-(2-(benzo[d]thiazol-2-yl)vinyl)phenyl)-3-(trifluoromethyl)benzenesulfonamide (CAS 478049-99-9)
- Plerixafor Impurity 3 (CAS CATO-C4X-11333)
- Relugolix Impurity 178 (CAS CATO-C4X-2429178)
- Dapagliflozin Impurity 152 (CAS 2459303-35-4)
- PF-06827443, 98% (HPLC) (CAS 2115022-67-6)
- 3-(Ethoxycarbonyl)-5-methyl-1-[3-(trifluoromethyl)phenyl]-4,5-dihydro-1h-pyrazole-5-carboxylic acid (CAS 1264046-90-3)
- Bis(4-tert-butylcyclohexyl)peroxydicarbonate (CAS 15520-11-3)
- 2-Amino-5-(aminomethyl)-4-(difluoromethyl)pyridin-3-ol (CAS 1806792-02-8)
- 5-(1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)thiophene-2-carbaldehyde (CAS 175202-93-4)
- (3-(Piperidin-4-yl)phenyl)methanamine (CAS 375854-54-9)
- Insulin Degludec Impurity 7 (CAS CATO-C4X-21577)
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