Trilostane Impurity 1 CAS CATO-C4X-21371
| CAS No. | CATO-C4X-21371 |
| Molecular Formula | C20H27NO3 |
| Molecular Weight | 329.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Trilostane Impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Trilostane Impurity 1 (CAS CATO-C4X-21371, C20H27NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Trilostane Impurity 1 (C20H27NO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 329.43 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C20H27NO3 |
| Molecular Weight | 329.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Trilostane Standards
- Trilostane Impurity 3 (CAS 20051-76-7)
- Trilostane (CAS 13647-35-3)
- Trilostane Impurity 10 (CAS CATO-C4X-213710)
- Trilostane Impurity 3 (CAS CATO-C4X-21373)
- Trilostane Impurity 7 (CAS 94152-62-2)
- Trilostane-d3 (CAS CATO-C4X-21378)
- Trilostane Impurity 1 (CAS 60413-79-8)
- Trilostane Impurity 2 (CAS 2301065-59-6)
Recommended Standards
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- Articaine EP Impurity J (CAS 1160919-46-9)
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- Isoprenaline Impurity 7 HCl (CAS CATO-C4X-277540)
- Methyl 2-(6-nitro-[1,1'-biphenyl]-3-yl)-2-phenylacetate (CAS 1923267-38-2)
- Mast Cell Degranulating (MCD) Peptide (CAS 32908-73-9)
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