Articaine EP Impurity J CAS 1160919-46-9
| CAS No. | 1160919-46-9 |
| Molecular Formula | C10H12BrNO3S |
| Molecular Weight | 306.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Articaine EP Impurity J (CAS 1160919-46-9) is a certified pharmaceutical impurity reference standard with the molecular formula C10H12BrNO3S and a molecular weight of 306.18 g/mol.
The molecular framework of Articaine EP Impurity J (C10H12BrNO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Articaine EP Impurity J meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12BrNO3S |
| Molecular Weight | 306.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Articaine Standards
- Articaine EP Impurity F (CAS CATO-C4X-191226)
- Articaine Impurity 16 (CAS CATO-C4X-191216)
- Articaine impurity 01 (CAS 161448-93-7)
- Articaine (CAS 23964-58-1)
- Articaine EP Impurity E (CAS 1796888-45-3)
- Articaine EP Impurity B (CAS 114176-52-2)
- Articaine Impurity 19 (CAS 2602451-78-3)
- Articaine EP Impurity A (CAS 1712677-79-6)
Recommended Standards
- n-Allyl-5-bromo-2-methoxybenzenesulfonamide (CAS 914235-06-6)
- 2,3-Bis(5-amino-2-chlorophenyl)propanenitrile (CAS 1272756-66-7)
- 8-Bromodibenzo[b,f][1,4]thiazepin-11(10H)-one (CAS 935433-69-5)
- 5-(Difluoromethyl)-1-phenyl-3-(trifluoromethyl)-1h-pyrazole-4-carboxylic acid (CAS 1394647-33-6)
- Plerixafor Impurity 32 DiHCl (CAS CATO-C4X-113332)
- Cefprozil Impurity 45 (CAS CATO-C4X-149245)
- Ambroxol impurity 108 (CAS 73220-00-5)
- Iguratimod Impurity 20 (CAS 544482-14-6)
- 5-Methoxy-6-(2-(pyrrolidin-1-yl)ethoxy)-1H-indole (CAS 399579-86-3)
- (4-Chloro-5,5-dimethyl-2-oxotetrahydrofuran-3-yl)methyl benzenesulfonate (CAS 154750-28-4)
- 5-Bromo-6-methyl-1,3-dihydro-2H-benzo[d]imidazol-2-one (CAS 634602-92-9)
- Methyl 2-amino-4-(1,1-difluoroethyl)-5-iodobenzoate (CAS 912575-29-2)
- 2-[(2,2-Dimethylpropyl)({[(9H-fluoren-9-yl)methoxy]carbonyl})amino]acetic acid (CAS 1935967-49-9)
- Tripeptide-10 citrulline (CAS 960531-53-7)
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