Fluralaner impurity 47 CAS CATO-C4X-218047
| CAS No. | CATO-C4X-218047 |
| Molecular Formula | C22H18ClF6N3O4 |
| Molecular Weight | 537.84 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Fluralaner impurity 47.
CATO supplies Fluralaner impurity 47 (CAS CATO-C4X-218047), a pharmacopoeial impurity reference standard (molecular formula C22H18ClF6N3O4, MW 537.84 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Fluralaner impurity 47 (C22H18ClF6N3O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Fluralaner impurity 47 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H18ClF6N3O4 |
| Molecular Weight | 537.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Fluralaner Standards
- Fluralaner Impurity 56 (CAS CATO-C4X-218056)
- Fluralaner Impurity 61 (CAS CATO-C4X-218061)
- Fluralaner impurity 33 (CAS CATO-C4X-218033)
- Fluralaner Impurity N6 (CAS 1352242-94-4)
- Fluralaner Impurity N5 (CAS 943436-93-9)
- Fluralaner Impurity 65 (CAS 1422465-94-8)
- Fluralaner Impurity 63 (CAS 3027861-23-7)
- Fluralaner Impurity 58 (CAS CATO-C4X-218058)
Recommended Standards
- 6'-Bromo-6-chloro-4,4'-diphenyl-[2,3'-biquinolin]-2'(1'H)-one (CAS 145317-44-8)
- 5-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-3-(3-methyl-5-oxo-1-phenyl-1,2,4-triazolidin-3-yl)-3aH,4H,5H,6H,6aH-pyrrolo[3,4-d][1,2]oxazole-4,6-dione (CAS 317822-46-1)
- 2-O-(tert-Butyldimethylsilyl)-3,5-O-(di-tert-butylsilanediyl)guanosine (CAS 401812-99-5)
- Bromo-Afatinib (CAS 1637254-93-3)
- Avibactam Impurity 154 (CAS CATO-C4X-1348154)
- Furosemide Impurity N5 (CAS 62971-57-7)
- Relugolix Impurity 215 (CAS CATO-C4X-2429215)
- 4-Bromo-7-chlorothieno[2,3-c]pyridine-2-carboxamide (CAS 870241-76-2)
- N'-(2-bromo-4-chlorobenzylidene)-4-methylbenzenesulfonohydrazide (CAS 1821332-73-3)
- 3-Nitro-2-(phenylsulfonyl)pyridine (CAS 188429-02-9)
- 5-Indazol-1-yl-3-oxo-pentanoic acid methyl ester (CAS 1229627-06-8)
- N-(5-(benzyloxy)-2,4-dichlorophenyl)-3-(2-fluoro-4-nitrophenoxy)thiophene-2-carboxamide (CAS 339015-59-7)
- 2-Methoxy-4-morpholinoaniline (CAS 209960-91-8)
- Cholecystokinin Octapeptide (1-4) (desulfated) (CAS 80790-40-5)
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