Vitamin A Impurity 21 CAS CATO-C4X-218721
| CAS No. | CATO-C4X-218721 |
| Molecular Formula | C72H120O4 |
| Molecular Weight | 1049.72 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Vitamin A Impurity 21 is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Vitamin A Impurity 21 (CAS CATO-C4X-218721, C72H120O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Vitamin A Impurity 21 (C72H120O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 1049.72 g/mol, it falls into the high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Vitamin A Impurity 21 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C72H120O4 |
| Molecular Weight | 1049.72 g/mol |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Vitamin Standards
- Vitamin A Impurity 18 (CAS CATO-C4X-218718)
- [13C7]-Vitamin B12 (CAS CATO-LCFD201937)
- Vitamin B12-[13C7] (CAS CATO-C4X-187415)
- Vitamin A EP Impurity A(Kitol Diacetate) (Mixture of Diastereomers) (CAS 13828-13-2)
- Vitamin D (CAS 859928-95-3)
- Vitamin A EP Impurity A(Kitol) (Mixture of Diastereomers) (CAS 22555-09-5)
- Vitamin D3 β-D-Glucuronide, >90% (CAS 57918-08-8)
- Pre-Vitamin D3 Decanoate (CAS 927822-18-2)
Recommended Standards
- Octreotide EP Impurity C (CAS 1546983-16-7)
- Neural-Cadherin (76-85) amide (chicken) (CAS 127650-08-2)
- Deamidated Etelcalcetide (CAS CATO-C4X-32474)
- Carbetocin Impurity 1 (CAS CATO-C4X-19111)
- Ondansetron EP Impurity H (CAS 99614-14-9)
- Iobitridol Impurity 12 (CAS CATO-C4X-317812)
- Valproate Impurity 49 (CAS 40239-27-8)
- methyl 3-chloro-5-methoxy-pyrazine-2-carboxylate (CAS 1823918-14-4)
- 1-Bromo-3-(tert-butyl)-5-cyclopropoxybenzene (CAS 1243360-14-6)
- Cis-3-penten-1-ol (CAS 764-38-5)
- 3-(3-Methoxy-5-methylphenyl)propanoic acid (CAS 22524-05-6)
- (E)-2-Methyl-4-(2,6,6-trimethylcyclohex-1-en-1-yl)but-1-en-1-yl formate (CAS 21730-91-6)
- Ivermectin EP Impurity H (CAS 71837-27-9)
- Tirzepatide Impurity 37 (CAS CATO-C4X-324037)
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