Roxadustat Impurity 148 CAS CATO-C4X-2213148
| CAS No. | CATO-C4X-2213148 |
| Molecular Formula | C21H20N2O5 |
| Molecular Weight | 380.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Roxadustat Impurity 148 (C21H20N2O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Roxadustat Impurity 148 (CAS CATO-C4X-2213148), a pharmacopoeial impurity reference standard (molecular formula C21H20N2O5, MW 380.39 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H20N2O5 |
| Molecular Weight | 380.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Roxadustat Standards
- Roxadustat Impurity 122 (CAS CATO-C4X-2213122)
- Roxadustat Impurity 35 (CAS 2370958-34-0)
- Roxadustat Impurity 174 (CAS CATO-C4X-2213174)
- Roxadustat Impurity 168 (CAS CATO-C4X-2213168)
- Roxadustat impurity 109 (CAS CATO-C4X-2213109)
- Roxadustat Impurity 95 (CAS CATO-C4X-221395)
- Roxadustat Impurity 139 (CAS CATO-C4X-2213139)
- Roxadustat Impurity 14 (CAS 808119-86-0)
Recommended Standards
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com