Roxadustat Impurity 46 CAS CATO-C4X-221346
| CAS No. | CATO-C4X-221346 |
| Molecular Formula | C24H23NO7S |
| Molecular Weight | 469.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Roxadustat Impurity 46 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Roxadustat Impurity 46 (CAS CATO-C4X-221346), a pharmacopoeial impurity reference standard (molecular formula C24H23NO7S, MW 469.51 g/mol) used for the identification and quantification of trace impurities in APIs.
Roxadustat Impurity 46 (C24H23NO7S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C24H23NO7S |
| Molecular Weight | 469.51 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Roxadustat Standards
- Roxadustat Impurity 45 (CAS CATO-C4X-221345)
- Roxadustat impurity 110 (CAS CATO-C4X-2213110)
- Roxadustat Impurity 7 (CAS 1455091-06-1)
- Roxadustat Impurity 47 (CAS CATO-C4X-221347)
- Roxadustat Impurity 140 (CAS CATO-C4X-2213140)
- Roxadustat Impurity 83 (CAS CATO-C4X-221383)
- Roxadustat Impurity 69 (CAS 2731734-05-5)
- Roxadustat Impurity 52 (CAS CATO-C4X-221352)
Recommended Standards
- 7-ACCA Impurity 9 (CAS CATO-C4X-23139)
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- Fluphenazine EP Impurity B (CAS 1476-79-5)
- (E)-5-(((4-fluorobenzyl)oxy)imino)-4-(4-methoxyphenyl)-2-(1H-pyrrol-1-yl)-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (CAS 477854-14-1)
- Clevidipine butyrate Impurity 25 (CAS 43107-08-0)
- Norethisterone EP Impurity F (CAS 96487-85-3)
- Atogepant Impurity 26 (CAS 957122-44-0)
- 2-Methyl-5-[(E)-[(thiophen-2-yl)methylidene]amino]benzonitrile (CAS 331459-71-3)
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- 3-Formyl-N,N-diisopropyl-2-phenylquinoline-4-carboxamide (CAS 650607-39-9)
- Ozefloxacin Impurity 10 (CAS 211576-36-2)
- 4-(2,6-Dimethylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine (CAS 886507-28-4)
- 4-Fluoro-2-methylpiperidine hydrochloride (CAS 1638768-09-8)
- Acetyl Tripeptide-1 (CAS 350595-76-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com