Betamethasone Impurity 142 CAS CATO-C4X-1437142

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-1437142
Molecular FormulaC44H57F2O12P
Molecular Weight846.89 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Betamethasone Impurity 142 CAS CATO-C4X-1437142 chemical structure

Description

Betamethasone Impurity 142 (CAS CATO-C4X-1437142) is a certified pharmaceutical impurity reference standard with the molecular formula C44H57F2O12P and a molecular weight of 846.89 g/mol.

Based on its molecular formula C44H57F2O12P, Betamethasone Impurity 142 contains a phosphate ester group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 846.89 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Betamethasone Impurity 142 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC44H57F2O12P
Molecular Weight846.89 g/mol
Purity97%+
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)15.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentF-containing

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