Calcitonin Impurity 20 CAS CATO-C4X-221820
| CAS No. | CATO-C4X-221820 |
| Molecular Formula | C10H7F2N3O |
| Molecular Weight | 223.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Calcitonin Impurity 20 (C10H7F2N3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 223.18 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies Calcitonin Impurity 20 (CAS CATO-C4X-221820), a pharmacopoeial impurity reference standard (molecular formula C10H7F2N3O, MW 223.18 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H7F2N3O |
| Molecular Weight | 223.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Calcitonin Standards
- Calcitonin Impurity 3 (CAS 22842-50-8)
- Calcitonin Impurity 17 (CAS CATO-C4X-221817)
- Calcitonin Impurity 18 (CAS CATO-C4X-221818)
- Calcitonin Impurity 6 (CAS 3680-13-5)
- Calcitonin impurity 22 (CAS 1430820-46-4)
- Calcitonin Impurity 19 (CAS CATO-C4X-221819)
- Calcitonin Impurity 2 (CAS 59854-14-7)
- Calcitonin Impurity 15 (CAS CATO-C4X-221815)
Recommended Standards
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- 4-(((tert-Butyldimethylsilyl)oxy)methyl)-5-methylthiazole-2-carboxylic acid (CAS 2057426-42-1)
- Ethyl 3-(Trifluoromethyl)pyrazole-5-carboxylate (CAS 129768-30-5)
- Sodium 2,3-dihydroxypropane-1-sulfonate (CAS 35396-47-5)
- Exenatide Acetate (CAS 141732-76-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com