Voriconazole Impurity 78 CAS 351042-08-5
| CAS No. | 351042-08-5 |
| Molecular Formula | C10H7F2N3O |
| Molecular Weight | 223.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Voriconazole Impurity 78 (CAS 351042-08-5) is a certified pharmaceutical impurity reference standard with the molecular formula C10H7F2N3O and a molecular weight of 223.18 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Voriconazole Impurity 78 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 223.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Voriconazole Impurity 78 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7F2N3O |
| Molecular Weight | 223.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Voriconazole Standards
- Voriconazole Impurity N2 (CAS 168479-96-7)
- Voriconazole Impurity 31 (CAS 1157981-64-0)
- Voriconazole Impurity 33 (CAS 1449785-88-9)
- Voriconazole Impurity 79 (CAS CATO-C4X-136679)
- Voriconazole EP Impurity E(Voriconazole Related Compound F) (CAS 5872-08-2)
- Voriconazole EP Impurity E (1R)-Isomer (CAS 35963-20-3)
- Voriconazole Impurity 86 (CAS CATO-C4X-136686)
- Voriconazole Impurity 72 (CAS CATO-C4X-136672)
Recommended Standards
- Calcitonin Impurity 20 (CAS CATO-C4X-221820)
- Apremilast Impurity N9 (CAS 67614-42-0)
- Ticagrelor Impurity 121 (CAS 378236-67-0)
- 1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarbonitrile (CAS 862574-87-6)
- Salbutamol Impurity 122 (CAS CATO-C4X-1176122)
- Tirofiban Impurity 68 (CAS CATO-C4X-125468)
- Ramelteon Impurity 53 (CAS CATO-C4X-262253)
- 1-(2,6-Dimethoxyphenyl)-2-nitropropene (CAS 78904-44-6)
- 5-Bromo-2-isopropylindoline (CAS 1368754-01-1)
- Di-sec-butyl oxalate (CAS 13784-89-9)
- (R)-tert-Butyl 3-(2-aminoethyl)pyrrolidine-1-carboxylate (CAS 1420537-04-7)
- (7R,8R,9S,13S,14S,17S)-7-(9-Bromononyl)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol 875573-67-4 (CAS 875573-67-4)
- Tert-butyl (2-chloro-5-nitrophenyl)carbamate (CAS 879614-90-1)
- Semaglutide impurity 48 (CAS CATO-C4X-222648)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com