Avatrombopag Impurity 99 CAS CATO-C4X-223499
| CAS No. | CATO-C4X-223499 |
| Molecular Formula | C29H33BrCl2N6O3S2 |
| Molecular Weight | 728.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Avatrombopag Impurity 99 (CAS CATO-C4X-223499, C29H33BrCl2N6O3S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Avatrombopag Impurity 99 (C29H33BrCl2N6O3S2) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Avatrombopag Impurity 99 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C29H33BrCl2N6O3S2 |
| Molecular Weight | 728.55 g/mol |
| Purity | 95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 2 |
Related Avatrombopag Standards
- Avatrombopag Impurity 113 (CAS CATO-C4X-2234113)
- Avatrombopag Impurity 48 (CAS CATO-C4X-223448)
- Avatrombopag Impurity 110 (CAS CATO-C4X-2234110)
- Avatrombopag Impurity 103 (CAS CATO-C4X-2234103)
- Avatrombopag Impurity 27 (CAS 3062079-49-3)
- Avatrombopag Impurity 61 (CAS CATO-C4X-223461)
- Avatrombopag Impurity 73 (CAS CATO-C4X-223473)
- Avatrombopag Impurity 140 (CAS CATO-C4X-2234140)
Recommended Standards
- (2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-iodo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl acetate (CAS 1374692-34-8)
- 5,8-Bis(5-bromothiophen-2-yl)-6,7-difluoro-2-((2-hexyldecyl)oxy)quinoxaline (CAS 2728678-37-1)
- 31183-11-6 CTK4G6518 ZINC 5,10,15,20-TETRA(4-PYRIDYL)-21 H,23 H-PORPHINE (CAS 31183-11-6)
- Iron, [[4,4′,4′′,4′′′-(21H,23H-porphine-5,10,15,20-tetrayl-κN21,κN22,κN23,κN24)tetrakis[benzenaminato]](2-)]-, (SP-4-1)- (CAS 71547-22-3)
- Relebactam Impurity 18 (CAS CATO-C4X-214418)
- Midazolam Impurity 1 (CAS 59468-90-5)
- Rupatadine impurity 17 (CAS CATO-C4X-102717)
- 5-acetamido-1H-pyrrole-2-carboxylic acid (CAS 869116-31-4)
- 2,6-di-tert-butyl-4-hydroxyphenyl acetate (CAS 32102-41-3)
- 2-(4-(Diethylamino)-2-methylphenyl)-6-methyl-2H-benzo[d][1,2,3]triazol-5-amine (CAS 708287-34-7)
- 4-[([1,1-Biphenyl]-4-ylmethoxy)methyl]piperidine (CAS 946680-54-2)
- 2-Amino-3-fluorobenzamide (CAS 187805-54-5)
- 4-((4-((Trimethylsilyl)ethynyl)-phenyl)ethynyl)phenol (CAS 910467-75-3)
- Tirzepatide Impurity 9 (CAS CATO-C4X-32409)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com