Epalrestat Impurity 12 CAS CATO-C4X-223612
| CAS No. | CATO-C4X-223612 |
| Molecular Formula | C17H17NO3S2 |
| Molecular Weight | 347.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Epalrestat Impurity 12 (CAS CATO-C4X-223612, C17H17NO3S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Epalrestat Impurity 12 (C17H17NO3S2) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Epalrestat Impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H17NO3S2 |
| Molecular Weight | 347.45 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Epalrestat Standards
- Epalrestat Impurity 51 (CAS CATO-C4X-223651)
- Epalrestat impurity 36 (CAS CATO-C4X-223636)
- Epalrestat Impurity 23 (CAS CATO-C4X-223623)
- Epalrestat impurity 48 (CAS CATO-C4X-223648)
- Epalrestat Impurity 16 (CAS CATO-C4X-223616)
- Epalrestat Impurity 62 (CAS 682775-70-8)
- Epalrestat impurity 47 (CAS CATO-C4X-223647)
- Epalrestat-d5 (CAS 2755644-33-6)
Recommended Standards
- (E,E)-Epalrestat Ethyl Ester （discontinue） (CAS CATO-C4X-223611)
- Sulindac Sulfide-d7 (CAS CATO-C4X-293018)
- Selexipag Impurity 65 (CAS CATO-C4X-196165)
- Nizatidine N-Oxide (CAS 102273-12-1)
- Spironolactone Impurity 19 (CAS CATO-C4X-134519)
- Rabeprazole Impurity 8 (CAS 935260-92-7)
- Acarbose EP Impurity F (CAS CATO-C4X-11736)
- N-(piperidin-4-yl)pyridin-3-amine dihydrochloride (CAS 1010827-02-7)
- 3-Cyclopropoxycyclobutanecarboxylic acid (CAS 2518152-53-7)
- N-Methyl-2-(trifluoromethyl)benzamide (CAS 171426-41-8)
- (2R,3S)-Methyl 2,3-dihydroxybutanoate (CAS 117406-91-4)
- 3-(Aminomethyl)cyclopentan-1-ol hydrochloride (CAS 1445951-54-1)
- (E)-N-(4-(2-(benzo[d]thiazol-2-yl)vinyl)phenyl)-3-methoxybenzamide (CAS 478049-96-6)
- Semaglutide impurity 200 (CAS CATO-C4X-2226200)
Why CATO?
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