Selexipag Impurity 65 CAS CATO-C4X-196165

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-196165
Molecular FormulaC22H25N3O
Molecular Weight347.45 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Selexipag Impurity 65 CAS CATO-C4X-196165 chemical structure

Description

CATO supplies Selexipag Impurity 65 (CAS CATO-C4X-196165), a pharmacopoeial impurity reference standard (molecular formula C22H25N3O, MW 347.45 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Selexipag Impurity 65 (C22H25N3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Selexipag Impurity 65 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC22H25N3O
Molecular Weight347.45 g/mol
AppearancePale yellow to yellow crystalline powder
Purity≥95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms3

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