Epalrestat impurity 29 CAS CATO-C4X-223629

Description

Compared with other compounds in its class, the molecular weight of 164.20 g/mol gives Epalrestat impurity 29 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Epalrestat impurity 29 (CAS CATO-C4X-223629) is a certified pharmaceutical impurity reference standard with the molecular formula C10H12O2 and a molecular weight of 164.20 g/mol.

The molecular framework of Epalrestat impurity 29 (C10H12O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Epalrestat impurity 29 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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