Nikethamide Impurity 12 CAS 27828-61-1

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.27828-61-1
Molecular FormulaC9H12N2O
Molecular Weight164.20 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Nikethamide Impurity 12 CAS 27828-61-1 chemical structure

Description

As a process- or degradation-related impurity, Nikethamide Impurity 12 (CAS 27828-61-1, C9H12N2O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Nikethamide Impurity 12 (C9H12N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. Its physicochemical properties are representative of its class; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Nikethamide Impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC9H12N2O
Molecular Weight164.20 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1964
Nitrogen Atoms2

Related Nikethamide Standards

Recommended Standards

Why CATO?