Maytansinoid Impurity 3 CAS CATO-C4X-22513
| CAS No. | CATO-C4X-22513 |
| Molecular Formula | C39H56ClN3O10S2 |
| Molecular Weight | 826.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Maytansinoid Impurity 3 (CAS CATO-C4X-22513, C39H56ClN3O10S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, Maytansinoid Impurity 3 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 826.46 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C39H56ClN3O10S2 |
| Molecular Weight | 826.46 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related Maytansinoid Standards
- Maytansinoid Impurity 14 (CAS CATO-C4X-22514)
- Maytansinoid Impurity 5 (CAS CATO-C4X-22515)
- Maytansinoid DM4 (CAS 799840-96-3)
- Maytansinoid DM4 Impurity 6 (CAS 138148-68-2)
- Maytansinoid DM4 (CAS 796073-69-3)
- Maytansinoid Impurity 6 (CAS CATO-C4X-22516)
- Maytansinoid DM1 (CAS 139504-50-0)
- Maytansinoid Impurity 7 (CAS CATO-C4X-22517)
Recommended Standards
- 5-((4,5-Diphenyl-1H-1,2,3-triazol-1-yl)methyl)-[1,1'-biphenyl]-3,4-diyl diacetate (CAS 5533-69-7)
- Iohexol-D5 (CAS 928623-33-0)
- 2-Phenyl-4,6-bis(3-(triphenylsilyl)phenyl)-1,3,5-triazine (CAS 2252416-90-1)
- 1,1,3,3-Tetramethyl-1,3-bis(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)disiloxane (CAS 71363-70-7)
- Cefixime Impurity 17 (CAS CATO-C4X-113917)
- Brexpiprazole Impurity 7 (CAS 913613-82-8)
- Oseltamivir Impurity 99 (CAS CATO-C4X-172099)
- Ethyl 2-(chloromethyl)-4-methylquinoline-3-carboxylate hydrochloride (CAS 1009306-52-8)
- Malathion D7 (CAS 352438-94-9)
- 4-Bromochlorobenzene-d4 (CAS 134415-42-2)
- Proparacaine Impurity 19 (CAS 343773-15-9)
- PFOS and PFOA Quality Control Substances in PVC (CAS CATO-CQCM100172)
- 1-Methyl-1,3-diazaspiro[4.4]Nonane-2,4-dione (CAS 1170110-01-6)
- Tau Peptide (306-336) (Repeat 3 Domain) trifluoroacetate salt (CAS 330456-26-3)
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