Polymyxin Impurity 40 TFA CAS CATO-C4X-225540
| CAS No. | CATO-C4X-225540 |
| Molecular Formula | C55H96N16O13 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Polymyxin Impurity 40 TFA (C55H96N16O13C2HF3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Polymyxin Impurity 40 TFA (CAS CATO-C4X-225540, C55H96N16O13C2HF3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Polymyxin Impurity 40 TFA under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C55H96N16O13 5*C2HF3O2 |
| Molecular Weight | 1303.49 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 16 |
Related Polymyxin Standards
- Polymyxin B - API Standards (CAS 1404-26-8)
- Polymyxin B Sulfate (CAS 1405-20-5)
- Polymyxin B nonapeptide TFA (CAS 2220175-42-6)
- Polymyxin Impurity 56 X Trifluoroacetate (CAS 3034660-94-8 (free base))
- Polymyxin E2 (CAS 30387-41-8)
- Polymyxin Impurity 20 (CAS 343979-23-7)
- Polymyxin B2 (CAS 34503-87-2)
- Polymyxin B2 XTFA Salt (CAS 34503-87-2 (free base))
Recommended Standards
- Phloroglucinol impurity 50 (CAS CATO-C4X-221750)
- Brivaracetam Impurity 41 (CAS CATO-C4X-200741)
- Biotin EP Impurity G Bromide (CAS 33719-11-8)
- Ethyl 2-cyano-3-[(2-ethylphenyl)amino]prop-2-enoate (CAS 1114823-95-8)
- 2-(tert-Butoxy)-5-hydroxybenzaldehyde (CAS 1243395-56-3)
- 2-(4-(((9H-fluoren-9-yl)methoxy)carbonyl)piperazin-1-yl)propanoic acid (CAS 1341588-25-7)
- Ethyl 4-oxo-4-(4-trifluoromethylphenyl)butyrate (CAS 155722-95-5)
- 2-(Cyclohexylmethyl)-6-(dimethylamino)phenol (CAS 1243364-95-5)
- 2-nitro-4-(pyridin-4-yl)aniline (CAS 59656-62-1)
- Semaglutide impurity 109 (CAS CATO-C4X-2226109)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com