Doxofylline impurity 45 CAS 96474-41-8
| CAS No. | 96474-41-8 |
| Molecular Formula | C11H14N4O4 |
| Molecular Weight | 266.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Doxofylline impurity 45 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Doxofylline impurity 45 (CAS 96474-41-8, C11H14N4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C11H14N4O4, Doxofylline impurity 45 contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 266.25 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C11H14N4O4 |
| Molecular Weight | 266.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Nitrogen Atoms | 4 |
Related Doxofylline Standards
- Doxofylline (CAS 69975-86-6)
- Doxofylline Impurity 14 (CAS 7029-96-1)
- Doxofylline Impurity 3 (CAS 1174289-18-9)
- Doxofylline Impurity 5 (CAS CATO-C4X-15135)
- Doxofylline Impurity 19 (CAS 254760-82-2)
- Doxofylline Impurity 6 (CAS 1429636-72-5)
- Doxofylline Impurity 7 (CAS CATO-C4X-15137)
- Doxofylline-d4 (CAS 1346599-13-0)
Recommended Standards
- Pentoxifylline Impurity 14 (CAS 6493-07-8)
- Sorbic acid Impurity 6 (CAS CATO-C4X-24236)
- Piperazine Impurity 64 (CAS 5854-18-2)
- Voriconazole Impurity 82 (CAS CATO-C4X-136682)
- Lacosamide EP Impurity B (R-Isomer) (CAS 1318777-54-6)
- Arotinolol Impurity 65 (CAS CATO-C4X-185465)
- All-rac-alfa-Tocopherol EP Impurity D (CAS CATO-C4X-119528)
- 3-{2-[4-(tert-Butyl)-2-chlorophenoxy]-ethyl}piperidine hydrochloride (CAS 1220033-99-7)
- 5-Chloro-2-ethoxybenzaldehyde (CAS 27682-64-0)
- Propyl 2-hydroxy-5-iodobenzoate (CAS 15125-86-7)
- 2-(4-Chlorophenyl)-2-(2,2-dimethylmorpholin-4-yl)acetonitrile (CAS 1258650-80-4)
- Ethyl 6-iodoquinoline-3-carboxylate (CAS 1416440-20-4)
- Ethyl (Z)-4-((dimethylamino)methylene)-2-methyl-5-oxo-4,5-dihydro-1H-pyrrole-3-carboxylate (CAS 34463-68-8)
- Semaglutide impurity 250 (CAS CATO-C4X-2226250)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com