Baricitinib Impurity 106 CAS CATO-C4X-2260106
| CAS No. | CATO-C4X-2260106 |
| Molecular Formula | C20H26N6O4S |
| Molecular Weight | 446.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 446.52 g/mol gives Baricitinib Impurity 106 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Baricitinib Impurity 106 (CAS CATO-C4X-2260106), a pharmacopoeial impurity reference standard (molecular formula C20H26N6O4S, MW 446.52 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Baricitinib Impurity 106 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 446.52 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H26N6O4S |
| Molecular Weight | 446.52 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Baricitinib Standards
- Baricitinib Impurity 118 (CAS CATO-C4X-2260118)
- Baricitinib Impurity 77 (CAS CATO-C4X-226077)
- Baricitinib Impurity 37 (CAS 2055723-13-0)
- Baricitinib Impurity 55 (CAS CATO-C4X-226055)
- Baricitinib Impurity 53 (CAS CATO-C4X-226053)
- Baricitinib Impurity 56 (CAS CATO-C4X-226056)
- Baricitinib Impurity 60 (CAS CATO-C4X-226060)
- Baricitinib Impurity 26 (CAS CATO-C4X-226026)
Recommended Standards
- Mizolastine Impurity 9 (CAS CATO-C4X-20069)
- 4-PREGNEN-11β, 21-DIOL-3, 20-DIONE 21-HEMISUCCINATE (CAS 10215-77-7)
- Sildenafil EP Impurity C (CAS 139755-91-2)
- Bis-propargyl-PEG8 (CAS 1092554-87-4)
- Buspirone EP Impurity F (CAS 2512210-24-9)
- Pregabalin Impurity 126 (CAS 2514962-85-5)
- Clindamycin Impurity 169 (CAS 887402-21-3)
- 2-([1,1'-Biphenyl]-4-yl)-4-(3-chlorophenyl)-6-phenyl-1,3,5-triazine (CAS 2085262-87-7)
- 2-Chloro-4-(piperazin-1-yl)aniline (CAS 1386950-70-4)
- 4-(3-Bromophenyl)tetrahydro-2h-pyran (CAS 1353855-35-2)
- 3-(Oct-1-en-3-yl)dihydrofuran-2,5-dione (CAS 101012-83-3)
- Vilanterol Impurity 23 (CAS CATO-C4X-193523)
- Ethyl (2S)-1-azabicyclo[2.2.1]heptane-2-carboxylate (CAS 2382793-76-0)
- Ganirelix 1-4 peptide (CAS 208599-57-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com