Baricitinib Impurity 127 CAS CATO-C4X-2260127
| CAS No. | CATO-C4X-2260127 |
| Molecular Formula | C16H27BN4O5S |
| Molecular Weight | 398.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Baricitinib Impurity 127 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Baricitinib Impurity 127 (CAS CATO-C4X-2260127), a pharmacopoeial impurity reference standard (molecular formula C16H27BN4O5S, MW 398.29 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Baricitinib Impurity 127 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 398.29 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C16H27BN4O5S |
| Molecular Weight | 398.29 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Baricitinib Standards
- Baricitinib Impurity 128 (CAS CATO-C4X-2260128)
- Baricitinib Impurity 50 (CAS 1187594-35-9)
- Baricitinib Impurity 47 (CAS CATO-C4X-226047)
- Baricitinib Impurity 136 (CAS CATO-C4X-2260136)
- Baricitinib Impurity 88 (CAS CATO-C4X-226088)
- Baricitinib Impurity 105 (CAS CATO-C4X-2260105)
- Baricitinib Impurity 17 (CAS 1187595-89-6)
- Baricitinib Impurity 81 (CAS CATO-C4X-226081)
Recommended Standards
- MEthyl 5-(4-bromophenyl)-1-(4-ethylphenyl)-2-methyl-1h-pyrrole-3-carboxylate (CAS 881040-08-0)
- 2-(1-((5-Bromothiophen-2-yl)sulfonyl)azetidin-3-yl)-1H-benzo[d]imidazole (CAS 1251682-13-9)
- Methyl 5-(4-bromophenyl)-1-(2-ethylphenyl)-2-methyl-1H-pyrrole-3-carboxylate (CAS 881040-07-9)
- tert-Butyl 8-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-1H-pyrido[4,3-b]indole-2(5H)-carboxylate (CAS 1253968-35-2)
- Mivacurium Chloride Impurity 10 (CAS 586959-47-9)
- Risedronate EP Impurity B (CAS 105462-23-5)
- Regorafenib Impurity 61 (CAS 327-78-6)
- 5-Bromo-1-(methylthio)-1,6-dihydropyrimidine (CAS 14001-67-4)
- 5,6-Dihydro-2H-[1,2,4]triazolo[3,4-c][1,4]oxazin-3(8H)-one (CAS 133365-36-3)
- (7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridin-6-yl)methanol (CAS 2179277-93-9)
- Clopidogrel Impurity 9 (CAS 532987-11-4)
- 8,9-Dimethoxy-2-methyl-5H,6H-[1,2,4]triazolo[1,5-c]quinazoline-5-thione (CAS 860610-66-8)
- Methyl 2-(hydroxymethyl)acrylate (CAS 15484-46-5)
- Tirzepatide Impurity 58 (CAS CATO-C4X-324058)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com