Baricitinib Impurity 48 CAS CATO-C4X-226048

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-226048
Molecular FormulaC14H14N6O2
Molecular Weight298.30 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Baricitinib Impurity 48 CAS CATO-C4X-226048 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 298.30 g/mol gives Baricitinib Impurity 48 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Baricitinib Impurity 48 (CAS CATO-C4X-226048) is a certified pharmaceutical impurity reference standard with the molecular formula C14H14N6O2 and a molecular weight of 298.30 g/mol.

Based on its molecular formula C14H14N6O2, Baricitinib Impurity 48 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 298.30 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Baricitinib Impurity 48 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC14H14N6O2
Molecular Weight298.30 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms6

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