Levocabastine Hydrochloride EP Impurity I CAS CATO-C4X-228925
| CAS No. | CATO-C4X-228925 |
| Molecular Formula | C26H29FN2O2 |
| Molecular Weight | 420.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Levocabastine Hydrochloride EP Impurity I (CAS CATO-C4X-228925) is a certified pharmaceutical impurity reference standard with the molecular formula C26H29FN2O2 and a molecular weight of 420.52 g/mol.
Structurally, Levocabastine Hydrochloride EP Impurity I (C26H29FN2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 420.52 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H29FN2O2 |
| Molecular Weight | 420.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Levocabastine Standards
- Levocabastine (CAS 79516-68-0)
- Levocabastine EP Impurity B (CAS CATO-C4X-22892)
- Levocabastine EP impurity E (CAS 105452-51-5)
- Levocabastine EP Impurity C (CAS CATO-C4X-22893)
- Levocabastine EP Impurity E (CAS CATO-C4X-22895)
- Levocabastine EP Impurity I (CAS CATO-C4X-22899)
- Levocabastine EP Impurity D (CAS CATO-C4X-22894)
- Levocabastine EP Impurity J (CAS CATO-C4X-228910)
Recommended Standards
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- Encorafenib Impurity 14 (CAS CATO-C4X-324914)
- Nafamostat Impurity 57 (CAS CATO-C4X-133257)
- (1R,5S)-1-methyl-3-azabicyclo[3.1.0]hexane;hydrochloride (CAS 2806714-67-8)
- 5-ethyl-2,5-dihydrofuran-2-one (CAS 2407-43-4)
- 2,5-Dihydroxybenzophenone (CAS 2050-37-5)
- 6-Bromo-4,4-dimethyl-1,2,3,4-tetrahydroquinoline (CAS 135631-91-3)
- 4,4-Dimethyl-1-(4-phenoxyphenyl)-1,4-dihydropyrimidine-2-thiol (CAS 1142212-97-2)
- Semaglutide Impurity 124 (CAS CATO-C4X-2226124)
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