Kukoamine Impurity 12 CAS CATO-C4X-229612
| CAS No. | CATO-C4X-229612 |
| Molecular Formula | C61H65N3O8 |
| Molecular Weight | 968.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Kukoamine Impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Kukoamine Impurity 12 (CAS CATO-C4X-229612, C61H65N3O8) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Kukoamine Impurity 12 (C61H65N3O8) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 31.0, corresponding to approximately 31 ring(s) or double-bond equivalent(s). With a molecular weight of 968.18 g/mol, it falls into the high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C61H65N3O8 |
| Molecular Weight | 968.18 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 31.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Kukoamine Standards
- Kukoamine Impurity 11 (CAS CATO-C4X-229611)
- Kukoamine Impurity 5 (CAS CATO-C4X-22965)
- Kukoamine Impurity 4 (CAS CATO-C4X-22964)
- Kukoamine Impurity 3 (CAS CATO-C4X-22963)
- Kukoamine Impurity 8 (CAS CATO-C4X-22968)
- Kukoamine Impurity 10 (CAS CATO-C4X-229610)
- Kukoamine B（~10% Acetic acid） (CAS 164991-67-7)
- Kukoamine A (CAS 75288-96-9)
Recommended Standards
- Paclitaxel EP Impurity K (CAS 148930-55-6)
- (2R,3R)methyl-2-(N-((2S,3R)-3-((9S)-9-((S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-methylbutanamido)-3-methoxy-5,10-dimethyl-4-(methylamino)-8-oxoundecanoyl)pyrrolidin-2-yl)propionamido)-3-methoxy-2-methyl-3-phenylpropanoate (CAS 863971-38-4)
- 2'-O-(tert-Butyldimethylsilyl) Paclitaxel (CAS 114655-02-6)
- Lenacapavir (CAS 2189684-44-2)
- Cefixime Impurity 15 (CAS CATO-C4X-113915)
- Semaglutide impurity 01 (CAS 1998701-31-7)
- Brivaracetam Impurity 152 (CAS CATO-C4X-2007152)
- 2-Isopropylisonicotinohydrazide (CAS 113548-81-5)
- 3-(3-Iodophenyl)-2-methylpropanoic acid (CAS 1936230-74-8)
- 4-Methyl-2-oxo-N-phenylimidazolidine-1-carboxamide (CAS 835-43-8)
- 3-((Tetrahydro-2H-thiopyran-3-yl)amino)benzonitrile (CAS 1341076-61-6)
- 1-Fmoc-3-(hydroxymethyl)piperidine (CAS 1341328-61-7)
- SSR 69071 (CAS 344930-95-6)
- Peptide 6A (H-6905.0005) (CAS 73549-32-3)
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