Tegoprazan Impurity 149 CAS CATO-C4X-2297149
| CAS No. | CATO-C4X-2297149 |
| Molecular Formula | C20H18F2N2O4 |
| Molecular Weight | 388.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Tegoprazan Impurity 149 (CAS CATO-C4X-2297149, C20H18F2N2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Tegoprazan Impurity 149 (C20H18F2N2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Tegoprazan Impurity 149 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H18F2N2O4 |
| Molecular Weight | 388.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Tegoprazan Standards
- Tegoprazan Impurity 142 (CAS CATO-C4X-2297142)
- Tegoprazan impurity 38 (CAS CATO-C4X-229738)
- Tegoprazan (CAS 942195-55-3)
- Tegoprazan Impurity 138 (CAS CATO-C4X-2297138)
- Tegoprazan Impurity 16 (CAS 942195-56-4)
- Tegoprazan impurity 46 (CAS CATO-C4X-229746)
- Tegoprazan Impurity 92 (CAS CATO-C4X-229792)
- Tegoprazan D6 (CAS CATO-C4X-229761)
Recommended Standards
- (2R,3R,4S,5R,6R)-2-(acetoxymethyl)-6-(allyloxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate (CAS 10343-15-4)
- N1-(4-methoxybenzyl)-N4-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)succinamide (CAS 329700-11-0)
- 3’-Demethylnobiletin (CAS 112448-39-2)
- Ethyl 2-({5-methoxy-4-[3-(trifluoromethyl)phenoxy]pyrimidin-2-yl}sulfanyl)acetate (CAS 338423-35-1)
- Famotidine EP Impurity G（Maleate） (CAS 76823-97-7（free base）)
- Almonertinib Impurity 1 (CAS 1899922-04-3)
- Drotaverine Impurity 7 (CAS CATO-C4X-24357)
- tert-Butyl 4-(((benzyloxy)carbonyl)amino)-5-methyl-3-oxohexanoate (CAS 1822810-13-8)
- 6-Chloro-4-hydroxy-1H-indazole-3-carbaldehyde (CAS 887569-72-4)
- (R)-1-(5-chloro-2-methylphenyl)ethan-1-amine (CAS 1213698-22-6)
- Bambuterol EP Impurity B (CAS 112935-92-9)
- 3-Benzyl-1-methyl-2-thioxoimidazolidin-4-one (CAS 562826-16-8)
- 6-Methoxy-2-Naphthaleneacetic Acid 1,1-dimethylethyl Ester (CAS 362523-40-8)
- Antifreeze Polypeptide 6 (winter flounder) trifluoroacetate salt (CAS 122604-16-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com