Niraparib Impurity 47 CAS CATO-C4X-232947
| CAS No. | CATO-C4X-232947 |
| Molecular Formula | C17H24BrNO4 |
| Molecular Weight | 386.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Niraparib Impurity 47 (CAS CATO-C4X-232947), a pharmacopoeial impurity reference standard (molecular formula C17H24BrNO4, MW 386.28 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C17H24BrNO4, Niraparib Impurity 47 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 386.28 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Niraparib Impurity 47 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H24BrNO4 |
| Molecular Weight | 386.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Niraparib Standards
- Niraparib Impurity 51 (CAS CATO-C4X-232951)
- Niraparib Impurity 13 (CAS 2381228-27-7)
- Niraparib Impurity 20 (CAS CATO-C4X-232920)
- Niraparib Impurity 45 (CAS 1476776-97-2)
- Niraparib Impurity 50 (CAS CATO-C4X-232950)
- Niraparib Impurity 41 (CAS CATO-C4X-232941)
- Niraparib Impurity 19 (CAS CATO-C4X-232919)
- Niraparib Impurity N19 (CAS 1038916-08-3)
Recommended Standards
- N-Acetal Bromopride (CAS 94135-22-5)
- Tert-butyl4-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridyl]-3,6-dihydro-2h-pyridine-1-carboxylate (CAS 1534381-85-5)
- N,N-DI-BOC-4-BROMOMETHYL-PHENYLAMINE (CAS 925889-68-5)
- 7-(benzenesulfonyl)-2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid (CAS 1638768-44-1)
- Isaaconazole Sulfate Impurity 2 (CAS CATO-C4X-123685)
- Levetiracetam impurity 8 (CAS CATO-C4X-10678)
- Peridine Impurity 10 HCl (CAS 4551-92-2)
- 5-Bromo-3-difluoromethoxy-2-fluorophenol (CAS 1804910-47-1)
- 2,5-Dichloropyrimidine (CAS 22536-67-0)
- 3-(4-Fluorophenyl)-5-methyl-2,4-dioxo-2,3,4,5-tetrahydro-1H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid (CAS 1105191-19-2)
- 4-Methyl-1H-benzo[d]imidazol-6-amine (CAS 177843-74-2)
- 1-(3-Fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol (CAS 1082437-10-2)
- Methyl 8-(5-hexylfuran-2-yl)octanoate (CAS 10038-16-1)
- Tirzepatide Impurity 50 (CAS CATO-C4X-324050)
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