2,5-Dichloropyrimidine CAS 22536-67-0
| CAS No. | 22536-67-0 |
| Molecular Formula | C4H2Cl2N2 |
| Molecular Weight | 148.98 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2,5-Dichloropyrimidine (CAS 22536-67-0), a certified reference material (molecular formula C4H2Cl2N2, MW 148.98 g/mol) for analytical method development and quality control.
The molecular framework of 2,5-Dichloropyrimidine (C4H2Cl2N2) is characterized by a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H2Cl2N2 |
| Molecular Weight | 148.98 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichloropyrimidine Standards
- 4,6-Dichloropyrimidine (CAS 1193-21-1)
- 4,5-dichloropyrimidine (CAS 6554-61-6)
- 2,5-Dichloropyrimidine-4-carbonitrile (CAS 1804892-77-0)
- 2,6-Dichloropyrimidine-4-carbonitrile (CAS 26293-93-6)
- 4,6-Dichloropyrimidine-5-carbonitrile (CAS 5305-45-3)
- 2,5-Dichloropyrimidine-4-carbaldehyde (CAS 1803728-57-5)
- 4,5-Dichloropyrimidine-2-carbaldehyde (CAS 1803849-33-3)
- 5,6-Dichloropyrimidine-4-carbaldehyde (CAS 1806317-35-0)
Recommended Standards
- 4,5-Dichloropyridazine (CAS 55271-49-3)
- Pazopanib Impurity 20 (CAS 3934-20-1)
- 2,3-Dichloropyrazine (CAS 4858-85-9)
- Resmetirom Impurity 1 (CAS 141-30-0)
- 4,5-Dichloro-N-[(pyrrolidin-2-yl)methyl]-1H-pyrrole-2-carboxamide (CAS 1825999-87-8)
- 1-Neopentyl-5-phenyl-1H-imidazole (CAS 116145-77-8)
- 2-((1H-1,2,4-triazol-1-yl)methyl)-3-chloro-5-(trifluoromethyl)pyridine (CAS 339099-82-0)
- 372942-43-3 Acetic-d3 acid, 2,5-dioxopyrrolidin-1-yl ester N-Acetoxy-d3-succinimide (CAS 372942-43-3)
- (1S,1''S)-2',2'''-[1,2- Ethanediylbis(oxy-2,1-ethanediyloxy)]bis[3,3'-diiodo[1,1'-binaphthalen]-2-ol] (CAS 1260243-73-9)
- 1,2,3,6-Tetrahydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2,2,2-trifluoroethyl)-pyridine (CAS 1219931-41-5)
- 1,4,5-Tris((4-(tert-butyl)phenyl)thio)anthracene-9,10-dione (CAS 82188-22-5)
- 139633-72-0 2-(7-methoxy-1-naphthyl)propanoic acid (CAS 139633-72-0)
- 4,6-Dimethyl-2-(methylamino)nicotinaldehyde (CAS 1935535-46-8)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com