Piperaquine Impurity 6 CAS CATO-C4X-23376
| CAS No. | CATO-C4X-23376 |
| Molecular Formula | C26H25Cl2N3O |
| Molecular Weight | 466.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 466.40 g/mol gives Piperaquine Impurity 6 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Piperaquine Impurity 6 (CAS CATO-C4X-23376), a pharmacopoeial impurity reference standard (molecular formula C26H25Cl2N3O, MW 466.40 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Piperaquine Impurity 6 (C26H25Cl2N3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Piperaquine Impurity 6 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H25Cl2N3O |
| Molecular Weight | 466.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Piperaquine Standards
- Piperaquine Impurity 9 (CAS 1233345-93-1)
- Piperaquine Impurity 3 (CAS CATO-C4X-23373)
- Piperaquine Impurity 10 (CAS CATO-C4X-233710)
- Piperaquine Impurity 5 (CAS CATO-C4X-23375)
- Piperaquine Base (CAS 4085-31-8)
- Piperaquine Phosphate (CAS 85547-56-4)
- Piperaquine Tetraphosphate (CAS 911061-10-4)
- Piperaquine Impurity 8 (CAS 918879-09-1)
Recommended Standards
- N-(3-cyano-4-((3-(trifluoromethyl)phenyl)thio)phenyl)-3-(trifluoromethyl)benzamide (CAS 477866-74-3)
- 5-Amino-6-bromo-N-((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methyl)chromane-8-carboxamide (CAS 947373-34-4)
- Dnp-Pro-Gln-Gly-OH (CAS 65080-33-3)
- N-(tert-butyl)-2-(2,6-dinitro-4-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide (CAS 318256-35-8)
- Faropenem Impurity 10 (CAS 106559-80-2)
- Ornidazole Impurity 47 (CAS CATO-C4X-133147)
- Prostaglandin Impurity N1 (CAS 36150-02-4)
- 8-amino-3,3-dimethyl-2,3,4,5-tetrahydro-1,5-benzoxazepin-4-one (CAS 1268033-45-9)
- 4-(Ethylamino)quinazoline-2-thiol (CAS 147408-62-6)
- 1-Propene, polymer with chloroethene (CAS 25119-90-8)
- 3-(3-Methoxyphenyl)propan-1-ol (CAS 7252-82-6)
- 2,3-Dimethoxybenzene-1-sulfonyl chloride (CAS 199873-36-4)
- Diniconazole (CAS 70217-36-6)
- Pheromone Biosynthesis Activating Neuropeptide (Helicoverpa assulta, Heliothis zea) (CAS 122071-54-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com