Opicapone Impurity 86 CAS CATO-C4X-240486
| CAS No. | CATO-C4X-240486 |
| Molecular Formula | C18H17ClN4O6 |
| Molecular Weight | 420.80 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Opicapone Impurity 86.
Opicapone Impurity 86 (CAS CATO-C4X-240486) is a certified pharmaceutical impurity reference standard with the molecular formula C18H17ClN4O6 and a molecular weight of 420.80 g/mol.
The molecular framework of Opicapone Impurity 86 (C18H17ClN4O6) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Opicapone Impurity 86 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H17ClN4O6 |
| Molecular Weight | 420.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Opicapone Standards
- Opicapone-d6 (CAS 923287-50-7(unlabelled))
- Opicapone impurity 32 (CAS CATO-C4X-240432)
- Opicapone impurity 36 (CAS CATO-C4X-240436)
- Opicapone Impurity 42 (CAS 1402714-38-8)
- Opicapone Impurity 74 (CAS CATO-C4X-240474)
- Opicapone Impurity 52 (CAS CATO-C4X-240452)
- Opicapone Impurity 46 (CAS CATO-C4X-240446)
- Opicapone Impurity N3 (CAS 1402714-41-3)
Recommended Standards
- Cyclotriacontane (CAS 297-35-8)
- (E)-4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)benzaldehyde O-(3-methoxybenzyl) oxime (CAS 1092343-78-6)
- N1-(2-methoxyphenyl)-2-{[5-chloro-2-nitro-4-(trifluoromethyl)phenyl]thio}acetamide (CAS 217490-28-3)
- 4-(6-Dimethylamino-4-trifluoromethyl-pyridin-2-yl)-benzoic acid 4-chloro-phenyl ester (CAS 1311279-75-0)
- Mirogabalin Impurity 8 (CAS CATO-C4X-29248)
- Atrasentan Impurity 166 (CAS 1059043-38-7)
- Chlorphenamine Impurity 61Maleic Acid (CAS 19428-44-5（free base）)
- 4-Chloro-N'-[(1E)-2-(4-chlorophenyl)-2-cyanoeth-1-en-1-yl]benzohydrazide (CAS 338403-16-0)
- 4-Bromo-1-ethyl-1h-pyrazol-3-amine (CAS 1006481-44-2)
- 7-Methyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine (CAS 1341038-09-2)
- N-benzyl-2-phenyl-4-(trifluoromethyl)pyrimidine-5-carboxamide (CAS 900019-74-1)
- 1-(4-(Dimethylamino)phenyl)-2-methylpropan-2-ol (CAS 37904-77-1)
- 1,2-dimethyl (1R,2R)-4-oxocyclohexane-1,2-dicarboxylate (CAS 159910-01-7)
- Autoinducing Peptide I trifluoroacetate salt (CAS 200010-29-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com