Upadacitinib Impurity 203 CAS CATO-C4X-2405203
| CAS No. | CATO-C4X-2405203 |
| Molecular Formula | C17H22BrNO3 |
| Molecular Weight | 368.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Upadacitinib Impurity 203 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Upadacitinib Impurity 203 (CAS CATO-C4X-2405203, C17H22BrNO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution, Upadacitinib Impurity 203 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 368.27 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C17H22BrNO3 |
| Molecular Weight | 368.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Upadacitinib Standards
- Upadacitinib Impurity 92 (CAS 2768445-23-2)
- Upadacitinib Impurity 162 (CAS CATO-C4X-2405162)
- Upadacitinib Impurity 145 (CAS CATO-C4X-2405145)
- Upadacitinib Impurity 3 (CAS CATO-C4X-24053)
- Upadacitinib Impurity 72 (CAS CATO-C4X-240572)
- Upadacitinib Impurity 24 (CAS 1869118-24-0)
- Upadacitinib (CAS 1310726-60-3)
- Upadacitinib Impurity 144 (CAS CATO-C4X-2405144)
Recommended Standards
- Trimethoxy(3,3,4,4,5,5,6,6,6-nonafluorohexyl)silane (CAS 85877-79-8)
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- 1H-Pyrazole, 1-[[1-[(phenylmethoxy)methyl]cyclopropyl]methyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- (CAS 1380308-82-6)
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- Cyclohexyl(4-((1-phenyl-1H-tetrazol-5-yl)methyl)piperazin-1-yl)methanone (CAS 1049477-70-4)
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- 4-[2-(Pentyloxy)ethyl]piperidine hydrochloride (CAS 1220030-31-8)
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- Osteogenic Growth Peptide (CAS 132996-61-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com