Lifitegrast Impurity 105 CAS CATO-C4X-2409105
| CAS No. | CATO-C4X-2409105 |
| Molecular Formula | C19H14ClNO4 |
| Molecular Weight | 355.77 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Lifitegrast Impurity 105 (CAS CATO-C4X-2409105) is a certified pharmaceutical impurity reference standard with the molecular formula C19H14ClNO4 and a molecular weight of 355.77 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Lifitegrast Impurity 105 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 355.77 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Lifitegrast Impurity 105 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H14ClNO4 |
| Molecular Weight | 355.77 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Lifitegrast Standards
- Lifitegrast Impurity 104 (CAS CATO-C4X-2409104)
- Lifitegrast Impurity 112 (CAS CATO-C4X-2409112)
- Lifitegrast Impurity 41 (CAS 851785-19-8)
- Lifitegrast Impurity 114 (CAS CATO-C4X-2409114)
- Lifitegrast Impurity 8 (CAS 851784-82-2)
- Lifitegrast Impurity 141 (CAS CATO-C4X-2409141)
- Lifitegrast Impurity 139 (CAS CATO-C4X-2409139)
- Lifitegrast Impurity 39 (CAS 1194864-16-8)
Recommended Standards
- Pemetrexed Impurity 67 (CAS CATO-C4X-172667)
- 1-(4-Chlorophenyl)-N-(2-methoxyphenyl)-4-oxo-1,4-dihydropyridazine-3-carboxamide (CAS 478063-26-2)
- TRPM4-IN-2 (CAS 667411-04-3)
- 1-Benzyl-N-(4-chlorophenyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxamide (CAS 338412-47-8)
- Celecoxib Impurity 41 (CAS 1803258-57-2)
- Apixaban Impurity 24 (CAS 1998079-16-5)
- Haloperidol Decanoate EP Impurity A (CAS 1797824-64-6)
- 4,5,6,7-Tetrahydrobenzo[b]thiophen-6-amine hydrochloride (CAS 444559-49-3)
- tert-Butyl 7-bromo-3,4-dihydro-1H-pyrido[3,4-b]indole-2(9H)-carboxylate (CAS 196203-96-0)
- Clindamycin Palmitate Impurity 107 (CAS CATO-C4X-1341107)
- N-n-Octyl-3,4-thiophenedicarboximide (CAS 773881-43-9)
- 5-Ethyl-5-(2-methylprop-2-en-1-yl)-2-sulfanyl-1,4,5,6-tetrahydropyrimidine-4,6-dione (CAS 115-56-0)
- 2-Bromo-5-(methylsulfonyl)pyridine (CAS 343262-51-1)
- Gastric Inhibitory Polypeptide (6-30) amide (human) (CAS 1139691-72-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com