Drotaverin Impurity 46 CAS CATO-C4X-243546
| CAS No. | CATO-C4X-243546 |
| Molecular Formula | C12H18O3 |
| Molecular Weight | 210.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Drotaverin Impurity 46.
As a process- or degradation-related impurity, Drotaverin Impurity 46 (CAS CATO-C4X-243546, C12H18O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Drotaverin Impurity 46 (C12H18O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Drotaverin Impurity 46 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H18O3 |
| Molecular Weight | 210.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Drotaverin Standards
- Drotaverin Impurity 74 (CAS CATO-C4X-243574)
- Drotaverin Impurity 50 (CAS 5409-31-4)
- Drotaverin Impurity 40 (CAS CATO-C4X-243540)
- Drotaverin Impurity 38 (CAS CATO-C4X-243538)
- Drotaverin Impurity 73 (CAS CATO-C4X-243573)
- Drotaverin Impurity 60 (CAS CATO-C4X-243560)
- Drotaverin Impurity 69 (CAS CATO-C4X-243569)
- Drotaverin Impurity 64 (CAS CATO-C4X-243564)
Recommended Standards
- Phloroglucinol impurity 59 (CAS 1521-62-6)
- Brivaracetam Impurity 67 (CAS 357338-13-7)
- Nabumetone Impurity 17 (CAS CATO-C4X-284817)
- Urapidil Impurity 43 (CAS CATO-C4X-192443)
- Ipragliflozin Impurity 12 (CAS CATO-C4X-188512)
- Tetrabenazine Impurity 46 (CAS CATO-C4X-274846)
- Sarpogrelate Impurity 25 (CAS CATO-C4X-291325)
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- 5-(Isopentylthio)-1H-1,2,4-triazol-3-amine (CAS 861925-01-1)
- D-Tyr1-Tirzepatide (CAS CATO-CPTD788928)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com