Phloroglucinol impurity 59 CAS 1521-62-6
| CAS No. | 1521-62-6 |
| Molecular Formula | C12H18O3 |
| Molecular Weight | 210.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C12H18O3, Phloroglucinol impurity 59 contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 210.27 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a process- or degradation-related impurity, Phloroglucinol impurity 59 (CAS 1521-62-6, C12H18O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Phloroglucinol impurity 59 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H18O3 |
| Molecular Weight | 210.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Phloroglucinol Standards
- Phloroglucinol Diacetyl ; 100 MG (CAS 116345-96-1)
- Phloroglucinol Impurity 57 (CAS 738614-23-8)
- Phloroglucinol Impurity 7 (CAS 203645-99-2)
- Phloroglucinol impurity 48 (CAS CATO-C4X-221748)
- Phloroglucinol impurity 49 (CAS CATO-C4X-221749)
- Phloroglucinol impurity 50 (CAS CATO-C4X-221750)
- Phloroglucinol Impurity 68 (CAS CATO-C4X-221768)
- Phloroglucinol impurity 58 (CAS 1521-61-5)
Recommended Standards
- Brivaracetam Impurity 67 (CAS 357338-13-7)
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- Drotaverin Impurity 74 (CAS CATO-C4X-243574)
- Bisoprolol Impurity 116 (CAS CATO-C4X-1247116)
- Tepotinib impurity 12 (CAS CATO-C4X-337412)
- Desmopressin Impurity 37 (CAS CATO-C4X-221537)
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- tert-Butyl 1-(hydroxymethyl)-3-oxa-8-azabicyclo[3.2.1]octane-8-carboxylate (CAS 1638651-85-0)
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- (R)-2-amino-3-phenylpropanamide hydrochloride (CAS 71666-94-9)
- Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 75976-10-2)
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