Labetalol Impurity 58 CAS CATO-C4X-246658
| CAS No. | CATO-C4X-246658 |
| Molecular Formula | C19H24N2O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Labetalol Impurity 58 (CAS CATO-C4X-246658) is a certified pharmaceutical impurity reference standard with the molecular formula C19H24N2O3HCl and a molecular weight of 364.87 g/mol.
Labetalol Impurity 58 (C19H24N2O3HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H24N2O3 HCl |
| Molecular Weight | 364.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Labetalol Standards
- Labetalol Impurity 29 (CAS 119021-71-5)
- Labetalol EP Impurity A (CAS 1391051-99-2)
- Labetalol Impurity 9 (CAS 22374-89-6)
- Labetalol EP Impurity C HCl (CAS 2386661-13-6)
- Labetalol-d5 HCl (CAS 2713514-78-2)
- Labetalol Impurity 23 (CAS 2724509-52-6)
- Labetalol Impurity 56 (CAS 2731858-23-2)
- Labetalol EP Impurity D HCl (CAS 32780-65-7)
Recommended Standards
- Peramivir Impurity 20 (CAS CATO-C4X-183320)
- Atrasentan Impurity 12 (CAS 1098784-86-1)
- Cefazolin Impurity 56 (CAS 106773-36-8)
- 6-Chloro-N-(3-chlorophenyl)-2H-chromene-3-carboxamide (CAS 338759-58-3)
- (S)-2-Chloro-3-phenylpropan-1-ol (CAS 127180-75-0)
- (S)-1-(2-nitrophenyl)ethan-1-amine (CAS 198756-82-0)
- 8-Methoxy-4-methylquinazoline (CAS 69674-28-8)
- 3,5-Bis(4-bromophenyl)-4-chloro-1h-pyrazole (CAS 1159988-75-6)
- 1-(2-Bromophenyl)pyrrolidin-2-one (CAS 7661-30-5)
- Liraglutide Impurity 20 TFA Salt (CAS CATO-C4X-199220)
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