Pyrroloquinoline Impurity 2 CAS CATO-C4X-24762
| CAS No. | CATO-C4X-24762 |
| Molecular Formula | C14H5ClN2O8 |
| Molecular Weight | 364.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Pyrroloquinoline Impurity 2 (CAS CATO-C4X-24762) is a certified pharmaceutical impurity reference standard with the molecular formula C14H5ClN2O8 and a molecular weight of 364.65 g/mol.
The molecular framework of Pyrroloquinoline Impurity 2 (C14H5ClN2O8) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C14H5ClN2O8 |
| Molecular Weight | 364.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Pyrroloquinoline Standards
Recommended Standards
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- 7-Chloro-2-(3-chlorophenyl)-3,8-dimethylquinoline-4-carbonyl chloride (CAS 1160257-10-2)
- 3-Bromo-4-chloro-2-methyl-1-(p-tolyl)-6,7-dihydro-1h-indole-5-carbaldehyde (CAS 326916-09-0)
- Glycyrrhizic Acid Impurity 20 (CAS CATO-C4X-253720)
- Pyridoxine impurity 83 (CAS CATO-C4X-187783)
- Flunixin Meglumine EP Impurity C (CAS 1452-94-4)
- (2R,3S)-1-tert-butyl 3-ethyl 2-(4-(cyclopentylamino)phenyl)piperidine-1,3-dicarboxylate (CAS 2316782-11-1)
- Methyl 3,5-Difluorobenzoate (CAS 216393-55-4)
- 1-(4-Chlorophenyl)-N-methyl-1-(pyrazin-2-yl)methanamine (CAS 1183164-38-6)
- (5-(5-Iodothiophen-3-yl)-1,3,4-thiadiazol-2-yl)methanamine (CAS 1526639-61-1)
- Benzofuran-2-yl(phenyl)methanone (CAS 6272-40-8)
- Ethyl 2-(4-methylpiperazin-1-yl)acetate (CAS 28920-67-4)
- [5-31]-Semaglutide (CAS CATO-C4X-2226263)
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